DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment awd and NME4

DIOPT Version :9

Sequence 1:	NP_001287625.1	Gene:	awd / 43739	FlyBaseID:	FBgn0000150	Length:	168	Species:	Drosophila melanogaster
Sequence 2:	NP_005000.1	Gene:	NME4 / 4833	HGNCID:	7852	Length:	187	Species:	Homo sapiens

Alignment Length:	139	Identity:	79/139 - (56%)
Similarity:	105/139 - (75%)	Gaps:	0/139 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KERTFIMVKPDGVQRGLVGKIIERFEQKGFKLVALKFTWASKELLEKHYADLSARPFFPGLVNYM 84
            :|||.:.||||||||.|||.:|:|||::||.||.:|...|.:.:|.:||.||..:||:|.|:.||
Human    37 RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYM 101

  Fly    85 NSGPVVPMVWEGLNVVKTGRQMLGATNPADSLPGTIRGDFCIQVGRNIIHGSDAVESAEKEIALW 149
            :|||||.|||||.|||:..|.|:|.|:.|::.||||||||.:.:.||:||.||:||.|::||.||
Human   102 SSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLW 166

  Fly   150 FNEKELVTW 158
            |...|||:|
Human   167 FQSSELVSW 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
awd	NP_001287625.1	PTZ00093	19..167	CDD:173387	79/139 (57%)
awd	NP_001287625.1	NDK	21..155	CDD:278749	75/133 (56%)
NME4	NP_005000.1	NDK	38..172	CDD:197791	75/133 (56%)
NME4	NP_005000.1	NDPk_I	38..167	CDD:239876	73/128 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61064
OrthoDB	1	1.010	-	-		D1334716at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100304
Panther	1	1.100	-	-	O	PTHR11349
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X354
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.930