DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1896 and PDCD7

DIOPT Version :9

Sequence 1:	NP_651886.1	Gene:	CG1896 / 43738	FlyBaseID:	FBgn0039870	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_005698.1	Gene:	PDCD7 / 10081	HGNCID:	8767	Length:	485	Species:	Homo sapiens

Alignment Length:	324	Identity:	73/324 - (22%)
Similarity:	117/324 - (36%)	Gaps:	96/324 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PHKKH---RLSEVKAKIQQVISSLGQL--------EQQSCGAGRDFDVHRAEELQRSTATLLDEL 57
            |.:.|   .|.||:|::.:.:..:.:|        |.::.||.......:...|:...|..|..|
Human   162 PQRTHAGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGAAWVLLYSQTAPLRAELAERLQPL 226

  Fly    58 DQVPGQQVVDEQKQRKRRRRLYRRSQHRVIRATVKSEAA-----EQKFS----------IEPPRN 107
            .|.........:.:|.|||||..|.:.|...|..::|||     ||:..          .|..|.
Human   227 TQAAYVGEARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRWRVKCVQEVEEKKRE 291

  Fly   108 TALEQAKHISL----RKQRDAASILETFDLLEKLCESR--GGDRAALC------QKLTH------ 154
            ..|:.|....|    :||.|...:::....||||.:.|  ...|..:|      :..||
Human   292 QELKAAADGVLSEVRKKQADTKRMVDILRALEKLRKLRKEAAARKGVCPPASADETFTHHLQRLR 356

  Fly   155 ----------------MRLVWRRVQEETQAGHV-----KESKKVASLESQWKAVFFG-------- 190
                            :|::....|||.:...:     ||.:|:...:.:.::..||
Human   357 KLIKKRSELYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKILLQKREIESKLFGDPDEFPLA 421

  Fly   191 --------------RSLPTPKLNKGKFLEIRSTWDSYI--SYCGRGSSIPRGWVLPPTKPTAQW 238
                          .|||.       .::||..||.|:  |...:|:.:|:||||||......|
Human   422 HLLEPFRQYYLQAEHSLPA-------LIQIRHDWDQYLVPSDHPKGNFVPQGWVLPPLPSNDIW 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1896	NP_651886.1	PDCD7	<160..242	CDD:292640	26/108 (24%)
PDCD7	NP_005698.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..133
PDCD7	NP_005698.1	PDCD7	191..481	CDD:318278	66/295 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000