DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eEF1alpha2 and AT1G07920

DIOPT Version :9

Sequence 1:	NP_524611.1	Gene:	eEF1alpha2 / 43736	FlyBaseID:	FBgn0000557	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_563799.1	Gene:	AT1G07920 / 837307	AraportID:	AT1G07920	Length:	449	Species:	Arabidopsis thaliana

Alignment Length:	461	Identity:	341/461 - (73%)
Similarity:	390/461 - (84%)	Gaps:	12/461 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKA 65
            |||||.||||||||||||||||||||||||.||||||.||:|||||.||.|.|||||||||||||
plant     1 MGKEKFHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKA 65

  Fly    66 ERERGITIDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKN 130
            |||||||||||||||||:|||.|:||||||||||||||||||||||||||:.:.||.|||||||:
plant    66 ERERGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKD 130

  Fly   131 GQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSEARYEEIKKEVSSYIKKIGYNPASVAFVPISG 195
            |||||||||||||||||:|...||||:|.|.||:|||:||.||||||:||:||||..:.||||||
plant   131 GQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIIKEVSSYLKKVGYNPDKIPFVPISG 195

  Fly   196 WHGDNMLEPSEKMPWFKGWSVERKEGKAEGKCLIDALDAILPPQRPTDKPLRLPLQDVYKIGGIG 260
            :.||||:|.|..:.|:|            |..|::|||.|..|:||:||||||||||||||||||
plant   196 FEGDNMIERSTNLDWYK------------GPTLLEALDQINEPKRPSDKPLRLPLQDVYKIGGIG 248

  Fly   261 TVPVGRVETGLLKPGMVVNFAPVNLVTEVKSVEMHHEALTEAMPGDNVGFNVKNVSVKELRRGYV 325
            ||||||||||::||||||.|||..|.|||||||||||:|.||:||||||||||||:||:|:||||
plant   249 TVPVGRVETGMIKPGMVVTFAPTGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVAVKDLKRGYV 313

  Fly   326 AGDSKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCHTAHIACKFSEIKEKCDRRTGKTTETE 390
            |.:||::|.:|||:||:|||::||||||.|||.|||||||:|||.|||||..|.|||:||..|.|
plant   314 ASNSKDDPAKGAANFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFSEILTKIDRRSGKEIEKE 378

  Fly   391 PKAIKSGDAAIIVLVPSKPLCVESFQEFPPLGRFAVRDMRQTVAVGVIKSVNFKETTSGKVTKAA 455
            ||.:|:|||.::.:.|:||:.||:|.|:|||||||||||||||||||||||:.|:.|..||||||
plant   379 PKFLKNGDAGMVKMTPTKPMVVETFSEYPPLGRFAVRDMRQTVAVGVIKSVDKKDPTGAKVTKAA 443

  Fly   456 EKAQKK 461
            .|...|
plant   444 VKKGAK 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eEF1alpha2	NP_524611.1	PTZ00141	1..450	CDD:185474	333/448 (74%)
AT1G07920	NP_563799.1	PTZ00141	1..446	CDD:185474	339/456 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	349	1.000	Domainoid score	I221
eggNOG	1	0.900	-	-		E1_COG5256
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	696	1.000	Inparanoid score	I134
OMA	1	1.010	-	-		QHG62187
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	1	1.000	-	-		FOG0000314
OrthoInspector	1	1.000	-	-		mtm1025
orthoMCL	1	0.900	-	-		OOG6_100227
Panther	1	1.100	-	-	O	PTHR23115
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X149
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840