DRSC/TRiP Functional Genomics Resources

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Protein Alignment eEF1alpha2 and hbs1

DIOPT Version :10

Sequence 1:NP_524611.1 Gene:eEF1alpha2 / 43736 FlyBaseID:FBgn0000557 Length:462 Species:Drosophila melanogaster
Sequence 2:NP_001342767.1 Gene:hbs1 / 2540430 PomBaseID:SPBC25B2.01 Length:592 Species:Schizosaccharomyces pombe


Alignment Length:445 Identity:169/445 - (37%)
Similarity:244/445 - (54%) Gaps:42/445 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 INIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAQEMGKGSFKYAWVLDKLKAERERGIT 72
            :::||.|||||||||..|.::::.|.|:.|:::|...||...|||||.|||:||..:.||.||:|
pombe   178 VHLVVTGHVDSGKSTMLGRIMFELGEINSRSMQKLHNEAANSGKGSFSYAWLLDTTEEERARGVT 242

  Fly    73 IDIALWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGTGEFEAGISKNGQTREHA 137
            :|:|...||:.|....|.|||||||||..||.|.|.||.|||:|.:....||.|..:||||||||
pombe   243 MDVASTTFESDKKIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHA 307

  Fly   138 LLAFTLGVKQLIVGVNKMDSTEPPYSEARYEEIKKEVSSY-IKKIGYNPASVAFVPISGWHGDNM 201
            .|...||:.:::|.|||:|...  :||.|::|||..||.: ||.:|:..::|.|||||...|.|:
pombe   308 YLLRALGISEIVVSVNKLDLMS--WSEDRFQEIKNIVSDFLIKMVGFKTSNVHFVPISAISGTNL 370

  Fly   202 L--EPSEKMPWFKGWSVERKEGKAEGKCLIDALDAILPPQRPTDKPLRLPLQDVYKIGGIGTVPV 264
            :  :.|:...|:|            |..|:.|||.::||::|..|||||.:.|||:.....|| .
pombe   371 IQKDSSDLYKWYK------------GPTLLSALDQLVPPEKPYRKPLRLSIDDVYRSPRSVTV-T 422

  Fly   265 GRVETGLLKPGMVVNFAPVNLVTEVKSVEMHHE-ALTEAMPGDNVGFNVKNVSVKELRRGYVAGD 328
            ||||.|.::...|:..........||:|..:.: :.|.|:.||.|...:.::.|.:||.|.:..:
pombe   423 GRVEAGNVQVNQVLYDVSSQEDAYVKNVIRNSDPSSTWAVAGDTVTLQLADIEVNQLRPGDILSN 487

  Fly   329 SKNNPPRGAADFTAQVIVLNHPGQIANGYTPVLDCH----TAHIACKFSEIKEKCDRRTGKTTET 389
            .: ||.|....|.|::...:..|.|.:|.|.||  |    ...::.|...:..|..|.       
pombe   488 YE-NPVRRVRSFVAEIQTFDIHGPILSGSTLVL--HLGRTVTSVSLKIVTVNNKRSRH------- 542

  Fly   390 EPKAIKSGDAAII---VLVPSKPLCVESFQEFPPLGRFAVRDMRQTVAVGVIKSV 441
                |.|...|::   .|....|||:.  :|.|.||||.:|....|||.|::|.:
pombe   543 ----IASRKRALVRISFLDGLFPLCLA--EECPALGRFILRRSGDTVAAGIVKEL 591

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
eEF1alpha2NP_524611.1 PTZ00141 1..450 CDD:185474 169/445 (38%)
hbs1NP_001342767.1 HBS1_N <34..81 CDD:462642
TEF1 175..591 CDD:444074 169/443 (38%)
Blue background indicates that the domain is not in the aligned region.

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