DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11563 and NOP16

DIOPT Version :9

Sequence 1:	NP_651884.1	Gene:	CG11563 / 43735	FlyBaseID:	FBgn0039868	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001243468.2	Gene:	NOP16 / 51491	HGNCID:	26934	Length:	232	Species:	Homo sapiens

Alignment Length:	205	Identity:	51/205 - (24%)
Similarity:	93/205 - (45%)	Gaps:	48/205 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KIRKNHARKRYRYNVNRKTMNKT--RSSTGKIKDPRMKKMWMEDQRVGTNFSEMGLAKDVNKAIA 64
            |.:....|:::.|:||||.:|:.  |.:..:|:...::..|...:.|..|.:|||||.|.|:|:.
Human     3 KAKGKTRRQKFGYSVNRKRLNRNARRKAAPRIECSHIRHAWDHAKSVRQNLAEMGLAVDPNRAVP 67

  Fly    65 IPSYKKDRLLAARVVNGFLEEELDEDERRVLGLKKPVVEEGPKRGHVVQELEQLASERADPEFR- 128
            :   :|.::.|.         |:|.:||....::||.|            |..|.:|.:.||.:
Human    68 L---RKRKVKAM---------EVDIEERPKELVRKPYV------------LNDLEAEASLPEKKG 108

  Fly   129 --LPKGVVKELSYFLNKHKFNYK-----AMVADRKNFGQWTWRQFRLKIRRFMS-IPEQFNVYLE 185
              |.:.::..:.|.:..|..:||     :.:..|:  |:|.|..:      |.| :|:     .|
Human   109 NTLSRDLIDYVRYMVENHGEDYKQSGKTSSILCRR--GRWRWSDW------FTSQLPQ-----AE 160

  Fly   186 QKKLPVGVKP 195
            ....||.::|
Human   161 ASPGPVKLEP 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11563	NP_651884.1	Nop16	9..173	CDD:401393	43/173 (25%)
NOP16	NP_001243468.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31		9/27 (33%)
NOP16	NP_001243468.2	Nop16	16..131	CDD:312799	35/138 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149952
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4706
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	68	1.000	Inparanoid score	I5342
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52410
OrthoDB	1	1.010	-	-		D1431164at2759
OrthoFinder	1	1.000	-	-		FOG0006842
OrthoInspector	1	1.000	-	-		oto90672
orthoMCL	1	0.900	-	-		OOG6_106310
Panther	1	1.100	-	-	LDO	PTHR13243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2683
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.840