Protein Alignment CstF50 and Cstf1

DIOPT Version :10

• Sequence 1: NP_651883.1
• Gene: CstF50 / 43734
• FlyBaseID: FBgn0039867
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001013179.1
• Gene: Cstf1 / 311670
• RGDID: 1309267
• Length: 431
• Species: Rattus norvegicus
• Alignment Length: 425
• Identity: 233/425 - (54%)
• Similarity: 291/425 - (68%)
• Gaps: 19/425 - (4%)

  Fly    12 VKNREILYRLMISQLMYDGLEKFAMELSMLVKADQ-CAPSERLLHVMIAGMQTLSDKDKT----- 70
            :|:|:.||:|:||||:|||....|..|...:|... |||||:|||::..||    :.|.|
  Rat     8 LKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGM----ENDDTAVQYA 68

  Fly    71 --NSDDVLP--GIDLEFEPEASALAPEPHSYETAYVTSHKQACRAGAFSCDGSLVATGSVDASIK 131
              .||.|.|  ||||||:.:...::||...|||.||||||..||...:|.||.|:||||.|||||
  Rat    69 IGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIK 133

  Fly   132 ILDVERMLAKSA-PEDI---EPGRE-QQGHPVIRTLYDHTDEVSYLEFHPKEHILASASRDGTVK 191
            |||.|||||||| |.::   |..:: .:.||||||||||.|||:.|.|||.|.||||.|||.|:|
  Rat   134 ILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLK 198

  Fly   192 LFDIAKPSVKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSAIPSQQHKA 256
            |||.:|||.|:|.|...:.|.:..:||||:||::.:||:|..||:||:.|.|||||..|..||..
  Rat   199 LFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTD 263

  Fly   257 GVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAHGGAAICSLEFTRNGKYLLSSGMDS 321
            .:..|.|:|:..:|.|||.||.||:|||:|.|||.|..:||.||.:||..|::|.||:||||.||
  Rat   264 AICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDS 328

  Fly   322 LVYLWELCTSRPIQTYTGAGTTGKQEHQTEAVFNHTEDYVLFPDEATTSLCSWNSRNGCRLTLNS 386
            :..|||:.|.|.:..|||||.:|:|.|:|:|||||||||:|.|||.|.|||.|:||...|..|.|
  Rat   329 VAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLS 393

  Fly   387 LGHNGPVRYITHSPNGPAFLTCSDDFRARFWYRRA 421
            ||||..||.|.|||..|.|:||||||||||||||:
  Rat   394 LGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRS 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CstF50	NP_651883.1	CSTF1_dimer	10..63	CDD:465240	25/51 (49%)
		WD40	98..417	CDD:238121	188/323 (58%)
		WD40 repeat	113..164	CDD:293791	33/55 (60%)
		WD40 repeat	170..208	CDD:293791	23/37 (62%)
		WD40 repeat	213..251	CDD:293791	19/37 (51%)
		WD40 repeat	259..295	CDD:293791	19/35 (54%)
		WD40 repeat	302..338	CDD:293791	17/35 (49%)
		WD40 repeat	392..417	CDD:293791	17/24 (71%)
Cstf1	NP_001013179.1	CSTF1_dimer	8..59	CDD:465240	25/54 (46%)
		WD40	100..424	CDD:238121	188/323 (58%)
		WD 1	106..145		27/38 (71%)
		WD40 repeat	116..171	CDD:293791	33/54 (61%)
		WD 2	171..210		26/38 (68%)
		WD40 repeat	177..215	CDD:293791	23/37 (62%)
		WD 3	215..254		18/38 (47%)
		WD40 repeat	220..259	CDD:293791	20/38 (53%)
		WD 4	260..301		21/40 (53%)
		WD40 repeat	266..301	CDD:293791	19/34 (56%)
		WD 5	303..343		21/39 (54%)
		WD40 repeat	309..345	CDD:293791	17/35 (49%)
		WD40 repeat	356..393	CDD:293791	23/36 (64%)
		WD 6	395..431		25/34 (74%)
		WD40 repeat	400..424	CDD:293791	17/23 (74%)