DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11550 and sec14l5

DIOPT Version :9

Sequence 1:	NP_651882.1	Gene:	CG11550 / 43731	FlyBaseID:	FBgn0039864	Length:	298	Species:	Drosophila melanogaster
Sequence 2:	XP_031749906.1	Gene:	sec14l5 / 493292	XenbaseID:	XB-GENE-953433	Length:	793	Species:	Xenopus tropicalis

Alignment Length:	284	Identity:	47/284 - (16%)
Similarity:	104/284 - (36%)	Gaps:	51/284 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VLKFLDWIHAQPHISDRFSEGEALHFFHACRYSMEVAKQVLDTNLTARTHLEEFFVNLDCERPEI 85
            :::...|:. :.|......:...|.|..|..::::.|:::|..:||.|......::....:.|::
Frog   259 LIRLRQWLQ-ETHKGKIPKDEHILRFLRARDFNIDKAREILCQSLTWRKQHHVDYLLSTWDPPQV 322

  Fly    86 RR-----------------------AMRTVSIVPLPGATPEGYRVILAKLDDLNTSNYNFADVMK 127
            ..                       .|.|..:|...|.......|:....:.|.....|    ..
Frog   323 LHDYYAGGWHHHDRDGRPLYVLRLGQMDTKGLVRALGEESLLRHVLSINEEGLRRCEEN----TN 383

  Fly   128 LYCMVFDFWMYEDGIQPGHVIVIDLKNTSLGHVARIGLLQMKKFLYYLQEAAAIRLIGFHFINIV 192
            ::......|          ..::||:..::.|:.|.|:..:.:.:..: ||.....:|...|...
Frog   384 IFGRPISSW----------TCLVDLEGLNMRHLWRPGVKALLRIIEVV-EANYPETLGRLLILRA 437

  Fly   193 PFMDKIL-ALMTPFM-----KKELTTVLHMHSDLKEFYKFVPQEMLPKEYGG----QLEEANVAK 247
            |.:..:| .|::||:     ||.|....:.:........::.:|::|...||    ::.|..:..
Frog   438 PRVFPVLWTLVSPFIDENTRKKFLIYAGNDYQGPGGLIDYIDKEVIPDFLGGECMCEVSEGGMVP 502

  Fly   248 EIYYK--KLLDNRKEMIEFETRHQ 269
            :..|:  :.|:|....:..||.:|
Frog   503 KALYRTPEELENDDIRLWTETIYQ 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11550	NP_651882.1	CRAL_TRIO	94..239	CDD:279044	27/154 (18%)
sec14l5	XP_031749906.1	PRELI	17..173	CDD:398400
		CRAL_TRIO_N	256..301	CDD:215024	7/42 (17%)
		CRAL_TRIO	326..490	CDD:395525	28/178 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910