Protein Alignment CG11550 and CLVS2

DIOPT Version :9

• Sequence 1: NP_651882.1
• Gene: CG11550 / 43731
• FlyBaseID: FBgn0039864
• Length: 298
• Species: Drosophila melanogaster
• Sequence 2: NP_001010852.2
• Gene: CLVS2 / 134829
• HGNCID: 23046
• Length: 327
• Species: Homo sapiens
• Alignment Length: 315
• Identity: 61/315 - (19%)
• Similarity: 132/315 - (41%)
• Gaps: 54/315 - (17%)

  Fly     1 MKEANLEDQYASFPEIRRPEVLKFLDWIHAQPHI----SD-----RFSEGEALHFFHACR---YS 53
            :::|.||  ....|:....::.:..|.:..:|.|    :|     ||......|.|.|.|   ..
Human    13 LEKARLE--LNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQY 75

  Fly    54 MEVAKQVLDTNLTARTHLEEFFVNLDCERPEIRRAMRTVSIVPLPGATPE----GYRVILAKLDD 114
            .|..:|.||           .|.:.....|.|::|::.    ..||....    |.::::....:
Human    76 FEYRQQNLD-----------MFKSFKATDPGIKQALKD----GFPGGLANLDHYGRKILVLFAAN 125

  Fly   115 LNTSNYNFADVMKLYCMVFDFWMYEDGIQ-PGHVIVIDLKNTSLGHVARIGLLQMKKFLYYLQEA 178
            .:.|.|...|:::...:..:..:.:..:| .|.|::||..|.:....:::....::..:..||::
Human   126 WDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDS 190

  Fly   179 AAIRLIGFHFINIVPFMDKILALMTPFMKKELTTVLHMH-SDLKEFYKFVPQEMLPKEYGGQLEE 242
            ...|..|.||:|...::..:..::.||:|::....:.:| ::|...::.:..|:||.|:||.|..
Human   191 FPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPP 255

  Fly   243 ANVAKEIYYKKLLDNRKEMIEFETRHQVN------------EKLRPGKAKNASDL 285
            .::.  .:.:.|||:     |::...:.|            ::|.|...|.:..:
Human   256 YDMG--TWARTLLDH-----EYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSV 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11550	NP_651882.1	CRAL_TRIO	94..239	CDD:279044	29/150 (19%)
CLVS2	NP_001010852.2	CRAL_TRIO_N	29..75	CDD:215024	10/45 (22%)
		SEC14	106..251	CDD:238099	27/144 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..327		3/17 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810