Protein Alignment Zmynd8 and zmynd8

DIOPT Version :10

• Sequence 1: NP_651881.2
• Gene: Zmynd8 / 43730
• FlyBaseID: FBgn0039863
• Length: 1664
• Species: Drosophila melanogaster
• Sequence 2: XP_068080416.1
• Gene: zmynd8 / 564460
• ZFINID: ZDB-GENE-041119-1
• Length: 1205
• Species: Danio rerio
• Alignment Length: 1334
• Identity: 333/1334 - (24%)
• Similarity: 543/1334 - (40%)
• Gaps: 344/1334 - (25%)

  Fly   300 SGEGESSLFSDASDTKTTTAKTP-------EEEAAERLALIYEEPPTPGWDP------------F 345
            |..|.|.  |::|.:.....|.|       ::.........|.:.|....||            :
Zfish    53 SSNGHSP--SESSPSPVKKKKKPGAVNSSKDQSELRHGPFYYVKQPALTTDPVDVVPQDGRNDFY 115

  Fly   346 CWKCRGCGKLMPCSKCLRSFHSYCVRPATTKFDSSWKCPEC------QVIEAAPKRLRRNGVSVD 404
            ||.|...|:::.|..|.|.:|:.|::.|... :..|.||||      :.||...|.:..  :::|
Zfish   116 CWVCHREGQVLCCELCPRVYHAKCLKLAAEP-EGDWFCPECEKITVAECIETQSKAMTM--LTLD 177

  Fly   405 LLSQLLSFALDRMKHVRGAHKLRSP--LEVFPLTYKKFFVNPVSFESLAQCIRNGAYQSTDEFLS 467
            .||.||.|||.:||. .|....:.|  ||..| .|.::..:.:...:|.:.|:...|.||:.||:
Zfish   178 QLSFLLKFALQKMKQ-PGTEPFQKPVSLEQHP-DYAEYIFHAMDICTLEKNIKKKMYGSTEAFLA 240

  Fly   468 EVKWIQHNALILDAGDAKVEQASKAVVKVCRQEANEIDTCPECYLNA-NSSDEWFVKVCRHPHLL 531
            :||||.||.:|.:.|:.|:...:|.:||:|..|.|||:.||||||:| ...|.||.:.|.:||.|
Zfish   241 DVKWILHNCIIYNGGNHKLTATAKVIVKICEHEMNEIEVCPECYLSACQKRDNWFCEPCSNPHPL 305

  Fly   532 LWAKLKGFPYWPAKAMGSSNSTLVNVRFFGKHDRAFVPVKDCFLYSAQNPNTQTSRRSARDLAEC 596
            :||||||||:|||||:...:.. |:.||||:||||:||:.:|:|.|.:.|.:....:|..:.|
Zfish   306 VWAKLKGFPFWPAKALRDKDGQ-VDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSA-- 367

  Fly   597 IREVEIHIDHIKRKIGAFNYAPYRTPYDPLEEQQQLEQMMPGVYAAIDRELEPAN---------- 651
            ::|:|:::::|::|.|.|||||:||||.|..:.|.|              |:|||
Zfish   368 MQEMEVYVENIRKKFGVFNYAPFRTPYTPDNQFQML--------------LDPANPSAGSVKPEK 418

  Fly   652 KTPLQFLIRKTADDKLSIVKKTKATESG-----NESDQSPSPTKKLSEVDVVSVTGSGCSD---- 707
            :..::|....||..||.:.|...::.||     :.:|...||....|...    |||....
Zfish   419 QEKIKFNFDVTASPKLLVGKSMVSSGSGTGRRISMTDMPRSPMSTNSSAH----TGSDGEQETAE 479

  Fly   708 --HSNVKSNNYE------------VISRSGESL----------------------TDSRCKVLLK 736
              |:.....:|.            ..||:|.:|                      |.|...:.|.
Zfish   480 KGHAKAALPHYSTGEESQDCTASPASSRAGSTLESPKPFHSPAPNTPVKQEKTPTTGSILNLNLD 544

  Fly   737 RK--SLAAKIVAESVETSEA-----VAPKR----------------------------------K 760
            |.  .:..|.::|||:..:.     .:|||                                  :
Zfish   545 RSKAEMDLKELSESVQQQQGAQPSLTSPKRQIRSRFQLNLDKTIESCKAQLGIDEISEDVYKGVE 609

  Fly   761 HSLSDASFTSESSEHKRKSKHARKQHDNQDNQIEEAEKTGQEPPKSPTISKQNENL-RDEENVIE 824
            ||.|:.|..|:||:.:..|:..:|..:.|:|:....:|..:||||..  ||.:... .|::...|
Zfish   610 HSDSEESDKSDSSDSEYGSEDEQKSKNGQNNKTTAEDKKEKEPPKKK--SKPSAAAGEDKDTSKE 672

  Fly   825 NAANDTSSASPVSASVVSVVELVRR-RQGVTITKIPREQQQTAEDTAAVPIPLPTAPPPKQNIPK 888
            ::|..::.|...:....|..:|:.: :.|:...|.|.|:.:.|          |.:|..::....
Zfish   673 SSATASTKAKAETGQKTSTPDLIAKDKSGMDSEKEPPEKLKAA----------PASPDAREKGKS 727

  Fly   889 GNEAANPKQSDVERQQEQLIKKVIPFIEIKTEVMSEPDDEGIEEASPANQPQTDQVPLQQETITA 953
            ..||:.|...||:...:...:.||...|          ::..:|...:.:.......|::.|.:.
Zfish   728 SEEASQPASVDVDMDSDSERELVIDLGE----------EQAGKERKRSRKDSAAVTALKEPTASK 782

  Fly   954 QPESQMPAAAPAPQPKPVDNAPFEEVRIKEEILSEDEMETEQSIVSRRLKSVPPMPLPMPPPPPL 1018
            ......|..:...||                          |:.|   |.|.|.|..|...|..:
Zfish   783 SEGKTTPITSSLTQP--------------------------QNTV---LSSSPTMKDPSQSPMAV 818

  Fly  1019 PPREESPATADSVRFVGDTTIQRVSQKQGGKSTDTGGKRKGVQQVPIAGIPQAPSPTHS--PLLS 1081
            |                                        :..:|:.|...:.|.|.|  |:.:
Zfish   819 P----------------------------------------LNIIPLTGAASSTSLTSSTLPIST 843

  Fly  1082 TAPSPSASPKPTSTLAVSKPPPP--------------PPPKGKSAS---HLQFRGKNDRIPTSPP 1129
            .:.:.|:||..|||:...:|..|              |..|.:::|   |:|      ::.....
Zfish   844 ASTASSSSPINTSTVKKQRPLLPRETVPVVQQAVVWNPSTKFQTSSQKWHMQ------KVQRQQQ 902

  Fly  1130 ATAPPATNTSSLLRSNMVVIPVEQGGSCNAHSPMTIPVPPLRAVSKNTLQNTSTGSTSSCVPSSV 1194
            ....|||....|.:......|.:|.                 .||.::....::.||......|:
Zfish   903 GQTQPATQAQVLTQVERNQQPQQQA-----------------QVSSSSSGQQASSSTRYQTRQSM 950

  Fly  1195 SMPPPLAGLSIPPVATPTSQEESITNSGQPVGLLASALNGTANDVLSSDSIPNDPITPGLATALS 1259
            .:                .::.|.|.|...|.|:.|                    ||..||.::
Zfish   951 KV----------------QKDSSHTTSTSAVTLVTS--------------------TPVSATIMA 979

  Fly  1260 EMLLHTGVPKLIARPRGALRSDGSQIYPSQAGPVSQKLKENAHKITDYFISVIEDTLSDMATGDQ 1324
            ...:.:......|         |....|:.:..|:..:.:..:||.|.....:.:..:|:.....
Zfish   980 GSTVSSSSTSATA---------GDFQIPTTSADVAADIAKYTNKIMDAIKGTMNEIYNDLTKSTS 1035

  Fly  1325 SVLQARIAGLSLENERLKQHYDRQINDLHRTSELMISEMRKTLEQEHKRVISELRQQNAIELMRA 1389
            ....|.|..|.:|.|:|:..:.::::::....||.::|||::||||.:|:::|:::|..:|..:|
Zfish  1036 GNTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERERIVAEVKKQMEMEKQQA 1100

  Fly  1390 VEEAKRKQWCANCMREAQLYCCWNTSYCDYPCQQLHWPGHSATCGQSVPPTIPVPPSVPTPIIEP 1454
            |:|.|:|||||||.:||..|||||||||||||||.|||.|..:|.||...:.....|..:..:
Zfish  1101 VDETKKKQWCANCRKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATSSQQEQESEGSTDV-- 1163

  Fly  1455 GRAKAKVATPTATPSITNPSPSSQIMRTVAACPS 1488
                    ||.| |...|..|:|. ..||::.|:
Zfish  1164 --------TPKA-PGQPNNGPNSP-RETVSSTPA 1187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zmynd8	NP_651881.2	PHD_PRKCBP1	345..386	CDD:277013	13/40 (33%)
		Bromo_RACK7	403..501	CDD:99940	36/99 (36%)
		PWWP_PRKCBP1	523..616	CDD:438988	40/92 (43%)
		zf-MYND	1399..1433	CDD:460312	25/33 (76%)
		PHA03247	<1427..1592	CDD:223021	16/62 (26%)
zmynd8	XP_068080416.1	TNG2	<15..158	CDD:227367	26/107 (24%)
		PHD_PRKCBP1	115..155	CDD:277013	13/40 (33%)
		Bromo_RACK7	176..274	CDD:99940	36/99 (36%)
		PWWP_PRKCBP1	297..387	CDD:438988	40/92 (43%)
		DUF3544	449..644	CDD:463452	35/198 (18%)
		AtpF	<1037..>1106	CDD:440475	22/68 (32%)
		zf-MYND	1110..1144	CDD:460312	25/33 (76%)