Protein Alignment Zmynd8 and zmynd8

DIOPT Version :10

• Sequence 1: NP_651881.2
• Gene: Zmynd8 / 43730
• FlyBaseID: FBgn0039863
• Length: 1664
• Species: Drosophila melanogaster
• Sequence 2: XP_012827102.2
• Gene: zmynd8 / 448494
• XenbaseID: XB-GENE-950478
• Length: 1272
• Species: Xenopus tropicalis
• Alignment Length: 1497
• Identity: 374/1497 - (24%)
• Similarity: 614/1497 - (41%)
• Gaps: 333/1497 - (22%)

  Fly   181 RSSSIPAPILDSDDDWQDEDIAWGVTTCRPRGRSMAFEDGERLANLNAE----DRNIVPAYSMAT 241
            |.|::||  |.|....::.:.....|...|:| |...|.|....:|..|    ::.:|....:.|
 Frog    15 RKSTLPA--LLSHAAGENMESGKAQTLISPQG-SQTQEAGNFSISLADEEIKTEQEVVEGMDVTT 76

  Fly   242 RCRSRSKTLSLSNSWSNDDKGPRRSNLRSENEEFAKK------HNAFLDRIIHDDRESELALNTS 300
              ||:...::.......|....::||..|......|:      |                    |
 Frog    77 --RSKGPAVAFPEGLPQDHGDSQQSNPGSTERPGQKRRFPSPQH--------------------S 119

  Fly   301 GEGESSLFSDASDTKTTTAKTP-------EEEAAERLALIY--EEPPTPGWDP------------ 344
            ..|.|.  .|:|.:.:...|.|       :|::..|....|  ::|.|.  ||
 Frog   120 SNGHSP--QDSSTSPSKKKKKPGVINSNNKEQSELRHGPFYYMKQPLTT--DPVDVIPQDGRNDF 180

  Fly   345 FCWKCRGCGKLMPCSKCLRSFHSYCVRPATTKFDSSWKCPEC------QVIEAAPKRLRRNGVSV 403
            :||.|...|:::.|..|.|.:|:.|:: .|.:.:..|.||||      :.||...|.:..  :::
 Frog   181 YCWVCHREGQVLCCELCPRVYHAKCLK-LTAEPEGDWFCPECEKITVAECIETQSKAMTM--LTI 242

  Fly   404 DLLSQLLSFALDRMKHVRGAHKLRSP--LEVFPLTYKKFFVNPVSFESLAQCIRNGAYQSTDEFL 466
            :.||.||.|||.:||. .|....:.|  ||..| .|.::..||:...:|.:.::...|..|:.||
 Frog   243 EQLSYLLKFALQKMKQ-PGTEPFQKPVSLEQHP-DYAEYIFNPMDLSTLEKNVKKKMYGCTEAFL 305

  Fly   467 SEVKWIQHNALILDAGDAKVEQASKAVVKVCRQEANEIDTCPECYLNA-NSSDEWFVKVCRHPHL 530
            :|.|||.||.:|.:.|:.|:.|.:|.::|:|..|.|||:.||||||.| ...:.||.:.|.:||.
 Frog   306 AEAKWILHNCIIYNGGNHKLTQTAKVIIKICEHEMNEIEVCPECYLAACQKRENWFCEPCSNPHP 370

  Fly   531 LLWAKLKGFPYWPAKAMGSSNSTLVNVRFFGKHDRAFVPVKDCFLYSAQNPNTQTSRRSARDLAE 595
            |:||||||||:|||||:...:.. |:.||||:||||:||:.:|:|.|.:.|.:....:|..:.|
 Frog   371 LVWAKLKGFPFWPAKALRDKDGQ-VDARFFGQHDRAWVPMNNCYLMSKEIPFSVKKTKSIFNSA- 433

  Fly   596 CIREVEIHIDHIKRKIGAFNYAPYRTPYDPLEEQQQLEQMMPGVYAAIDRELEPANKTPLQFLIR 660
             ::|:|:::::|:::.|.|||||:||||.|..:.|.|  :..|..:|...:.|...|..|.|  .
 Frog   434 -MQEMEVYVENIRKRFGVFNYAPFRTPYTPNNQYQML--LDTGNPSAGTAKTEKQEKIKLNF--D 493

  Fly   661 KTADDKLSIVKKTKATESGNE----SDQSPSPTKKLSEVDVVSVTGSGCSDHSN--VKSNNYEVI 719
            .||..|: ::.|.....||..    :|...||....|.|.    |||.....::  |.|:::
 Frog   494 MTASPKI-LMSKPMLNSSGGRRISLTDMPRSPMSTNSSVH----TGSDVEQEADKKVASSHF--- 550

  Fly   720 SRSGESL--TDSRCKVLLKRKSLAAKIVAESVETSE----AVAPKRKHSLSDASFTSESSEHKRK 778
            |.|.||:  ||         ||.|:   .:|.:...    |.:||   ..|..|.|..||:.:|.
 Frog   551 SASEESMDFTD---------KSTAS---PKSTKVGHGGNIADSPK---PFSPQSSTPVSSKQERS 600

  Fly   779 SKHARKQHDNQDN-----QIEEAEKTGQEPPKSPTISKQNENLRDEENVIENAANDTSSASPVSA 838
            :......:.|.|.     .::|..::..:...:|.||.:.: :|                |....
 Frog   601 ATTGSILNLNLDRSKAEMDLQELSESVLQSTPTPLISPKRQ-IR----------------SRFQL 648

  Fly   839 SVVSVVELVRRRQGVTITKIPREQQQTAEDTAAVPIPLPTAPPPKQNIPKGNEAANPKQSDVERQ 903
            ::...:|..:.:.|  |.:||.:.....|.:.:                :.:|..:...|:....
 Frog   649 NLDKTIESCKAQLG--INEIPEDAYTAVEHSDS----------------EESEKTDSSDSEYVSD 695

  Fly   904 QEQLIKKVIPFIEIKTEVMSEPDDEGIEEAS--------PANQPQTDQVPLQQETITAQPESQMP 960
            :|...|.....:|.|..|.:|.:.......|        ||:....|..   :.|.||..::..|
 Frog   696 EEHKTKNEQEDVEDKESVKAEKESSSSSSVSSLKKKAKTPASADTKDNA---KSTSTATEKADTP 757

  Fly   961 A------AAPAPQPKPVDNAPFEEVRIKEEILSEDEMETEQSIVSRRLKSVPPMPLPMPPPPPLP 1019
            :      .||....:...:||..   .||::..:||.::            |.:.|.:
 Frog   758 SKDKSGPEAPKEVTERTKSAPHS---AKEKLKGKDETDS------------PTVRLGL------- 800

  Fly  1020 PREESPATADSVRFVGDTTIQRVSQKQGGKSTDTGGKRKGVQQVPIAGIPQAPSPTHSPLLSTAP 1084
               :|.:.::.|..:|:....|..:|...::.:|..|::               .:.||.:|.:.
 Frog   801 ---DSDSESELVIDLGEDQSGREGRKHKKETKETPAKQQ---------------ESKSPAVSNSN 847

  Fly  1085 SPSASPKPTSTLAVSKPPPPPPPKGKSASHLQFRGKNDRIPTSPPATAP-PATNTSSLLRSNMVV 1148
            |.|....|..|.:.::..|               .....:.||..|..| .|..|.|.::....:
 Frog   848 SQSQPETPILTRSATQAIP---------------AVGVTVTTSALAAVPVAAAATGSPVKKQRPL 897

  Fly  1149 IPVEQGGSCNAHSPMTIPVPPLRAVSKNTLQNTSTGSTSSCVPSS------------VSMPPPLA 1201
            :|.|           |:|          |:|.....|:|....||            ....|..|
 Frog   898 LPKE-----------TVP----------TVQRVVWNSSSKFQTSSQKWHMQKVQRQQQQQQPATA 941

  Fly  1202 GLSIPPVATPTSQEESITNSGQPVGLLASALNGTANDVLSSDSIPNDPITPGLATALSEMLLHTG 1266
            ..:....|.|.|...:...:.|.|                 .::....:||  ||..|.:.|.|.
 Frog   942 AAAAAAAAVPQSPTGTRYQTRQAV-----------------KAVQQKDVTP--ATTTSTITLVTN 987

  Fly  1267 VPKL--IARPRGALRSDGSQIYP--SQAGPVSQKLKENAHKITDYFISVIEDTLSDMATGDQSVL 1327
            .|.|  :..|...:.:..|...|  :.:..|:..:.:...|:.|.....:.:..:|::.......
 Frog   988 APPLTVVPSPANTVNAPVSTDLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 1052

  Fly  1328 QARIAGLSLENERLKQHYDRQINDLHRTSELMISEMRKTLEQEHKRVISELRQQNAIELMRAVEE 1392
            .|.|..|.:|.|:|:..:.:::.::....||.::|||::||||..|:|:|:::|..:|..:||:|
 Frog  1053 IAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQTELEKQQAVDE 1117

  Fly  1393 AKRKQWCANCMREAQLYCCWNTSYCDYPCQQLHWPGHSATCGQSVPPTIPVPPSVPTPIIEPGRA 1457
            .|:|||||||.:||..|||||||||||||||.|||.|..:|.||...|...|        :|..:
 Frog  1118 TKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATATQQEP--------DPELS 1174

  Fly  1458 KAKVATPTAT--PSITNPSPSSQIMRTVAACPSAPPSANASSSKKWPPMMTLMNQSNQEAMLKLP 1520
            ..|...||::  |..|..|             |.|.......||:...:.|.:.......::::.
 Frog  1175 TDKSGQPTSSIQPQSTETS-------------STPKEKEGDKSKESVTIATGVPSCQPIKLVQVS 1226

  Fly  1521 ATTYLRPVVSTTMTAPVTAPQPANNNSTNVIMAPTPPPGNNLATIISAQRNPPNYNAKHPNPAMP 1585
            .||...|....|:|.|             |:::||   ...:|.....|         :....||
 Frog  1227 QTTTFIPTTQPTITIP-------------VVVSPT---AGTMAVRTGVQ---------YVQTTMP 1266

  Fly  1586 VQ 1587
            ||
 Frog  1267 VQ 1268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zmynd8	NP_651881.2	PHD_PRKCBP1	345..386	CDD:277013	13/40 (33%)
		Bromo_RACK7	403..501	CDD:99940	35/99 (35%)
		PWWP_PRKCBP1	523..616	CDD:438988	39/92 (42%)
		zf-MYND	1399..1433	CDD:460312	25/33 (76%)
		PHA03247	<1427..1592	CDD:223021	34/163 (21%)
zmynd8	XP_012827102.2	TNG2	<118..224	CDD:227367	30/130 (23%)
		PHD_PRKCBP1	181..221	CDD:277013	13/40 (33%)
		Bromo_RACK7	242..340	CDD:99940	35/99 (35%)
		PWWP_PRKCBP1	363..453	CDD:438988	39/92 (42%)
		DUF3544	513..710	CDD:463452	48/253 (19%)
		AtpF	<1053..>1120	CDD:440475	23/66 (35%)
		zf-MYND	1124..1158	CDD:460312	25/33 (76%)