Protein Alignment Zmynd8 and prkcbp1l

DIOPT Version :10

• Sequence 1: NP_651881.2
• Gene: Zmynd8 / 43730
• FlyBaseID: FBgn0039863
• Length: 1664
• Species: Drosophila melanogaster
• Sequence 2: NP_955935.3
• Gene: prkcbp1l / 323479
• ZFINID: ZDB-GENE-030131-2199
• Length: 1131
• Species: Danio rerio
• Alignment Length: 1272
• Identity: 339/1272 - (26%)
• Similarity: 536/1272 - (42%)
• Gaps: 283/1272 - (22%)

  Fly   300 SGEGESSLFSDASDTKTTTAKTP------EEEAAERLA-LIYEEPPTPGWDP------------F 345
            |..|.|.  ||.|.:.|...|.|      :::...|.. ..|.:.|....||            :
Zfish    48 SSNGHSP--SDTSPSPTKKKKKPGLVNSNKDQCELRHGPFYYVKQPALTTDPVDVVPQDGRNDFY 110

  Fly   346 CWKCRGCGKLMPCSKCLRSFHSYCVRPATTKFDSSWKCPEC------QVIEAAPKRLRRNGVSVD 404
            ||.|...|:::.|..|.|.:|:.|::.|... :..|.||||      :.||...|.:..  ::::
Zfish   111 CWVCHREGQVLCCELCPRVYHAKCLKLAAEP-EGDWFCPECEKITVAECIETQSKAMTM--LNLE 172

  Fly   405 LLSQLLSFALDRMKHVRGAHKLRSP--LEVFPLTYKKFFVNPVSFESLAQCIRNGAYQSTDEFLS 467
            .||.||.|||.:||. .|....:.|  |:..| .|.::..:|:...:|.:.|:...|..|:.||:
Zfish   173 QLSYLLKFALQKMKQ-PGTEPFQKPVSLDQHP-DYAEYIFHPMDLSTLEKNIKKKMYGCTEAFLA 235

  Fly   468 EVKWIQHNALILDAGDAKVEQASKAVVKVCRQEANEIDTCPECYLNA-NSSDEWFVKVCRHPHLL 531
            :||||.||.:|.:.|:.|:...:|.:||:|..|.|||:.||||||:| ...|.||.:.|..||.|
Zfish   236 DVKWILHNCIIYNGGNHKLTATAKVIVKICEHEMNEIEVCPECYLSACQKRDNWFCEPCSQPHPL 300

  Fly   532 LWAKLKGFPYWPAKAMGSSNSTLVNVRFFGKHDRAFVPVKDCFLYSAQNPNTQTSRRSARDLAEC 596
            :||||||||:|||||:...:.. |:.||||:||||:||:.:|:|.|.:.|.:....:|..:.|
Zfish   301 VWAKLKGFPFWPAKALRDKDGQ-VDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSA-- 362

  Fly   597 IREVEIHIDHIKRKIGAFNYAPYRTPYDPLEEQQQLEQMMPGVYAAIDRELEPANKTPLQFLIRK 661
            ::|:|::::::::|.|.|||||:||.|.|    ..|.||:.          :|.|  |.:..::.
Zfish   363 MQEMEVYVENVRKKYGVFNYAPFRTAYTP----NNLFQMLQ----------DPNN--PKKGTVKS 411

  Fly   662 TADDKLSIVKKTKATESGNESDQSPSPTKKLSEVDVVSVTGSGCSDHSNVKSNNYEVISRSGESL 726
            ...||:..           ..|.:.|| |.|....|:| .|.||.                 .|:
Zfish   412 EKQDKVKF-----------NFDMTASP-KMLLGKSVMS-GGGGCR-----------------ISV 446

  Fly   727 TDSRCKVLLKRKSLAAKIVAESVETSEAVAPKRKHSLSDASFTSESSEH--KRKSKHARKQHDNQ 789
            ||      :.|..::         |:.:|     |:.||.    |..|.  |..|.|.....|:.
Zfish   447 TD------MPRSPMS---------TNSSV-----HTGSDL----EQDERGAKMSSSHCSAGEDSM 487

  Fly   790 DNQIEEAE-KTGQEPPKSPTISKQNENLRDEENVIENAANDTSSASPVSASVVSVVELVRRRQGV 853
            |.....|. ||...|....|...:.|.......:: |...|...|.      :.:.||
Zfish   488 DCTASPASLKTSGSPKPLLTTPVKQERSSGTGGIL-NLNLDRVKAE------MDLKEL------- 538

  Fly   854 TITKIPREQQQTAEDTAAVPIPLPTAP-PPKQNIPKG----------NEAANPKQSDVERQQEQL 907
              ::..::|||..:..|:|   |.|:| .|.:::.|.          ||.::.....||....:.
Zfish   539 --SEAVQQQQQQQQQGASV---LLTSPKKPTRSLDKTIESCKAQLGINEISDDMCGGVEHSDSED 598

  Fly   908 IKKVIPFIEIKTEVMSEPDDEGIEEASPANQPQTDQV-------PLQQETITAQPESQMPAAAPA 965
            ..|.         ..|:.::...:|..|.|....:.|       |....|.....:|.....|..
Zfish   599 SDKC---------DSSDSEEMSDDEQKPKNTNHNNSVHKDSKKRPRTLSTQGQDQDSSTTGGASG 654

  Fly   966 PQPKPVDNAPFEEVRIKEEILSEDEMETEQSIVSRRLKSVPPMPLPMPPPPPLPPREESPATADS 1030
            .:.|..|      .:.||:.....|.::::       ||         .|.|...:|::.:..|
Zfish   655 GEKKTSD------PQTKEKSSGGAEKDSQE-------KS---------KPQPQSKKEKTKSAKD- 696

  Fly  1031 VRFVG-----DTTIQR-----VSQKQGGKSTDTGGKRKGVQQVPIAGIPQAPSPTHSPLL----- 1080
            ||..|     |:..:|     :.::|||:.     |:|..:..|.|.:   .:|....::
Zfish   697 VRTAGSEPDLDSDSERELVIDLGEEQGGRE-----KKKAKRDAPTAPV---STPKDQTVVKTDGK 753

  Fly  1081 -STAPSPSASPKPTSTLAVSKPPPPPPPKGKSASHLQFRGKNDRIPTSPPATAP-PATNTSSLLR 1143
             ||:.|.||||   ||...|.....|.||..::|.::           |||..| |:|..||
Zfish   754 SSTSTSVSASP---STDTTSSSSSNPAPKDAASSAIK-----------PPAAVPAPSTTQSS--- 801

  Fly  1144 SNMVVIPVEQGGSCNAHSPMTIPV-----PPLRAVSKNTLQNTSTGSTSS---CVPSSVSMPPPL 1200
            |:....||       :..|.|..|     |.|...|....|..:|.|.::   .|........|.
Zfish   802 SSSAAQPV-------STVPSTASVVKKQRPLLPKESTQPAQRPATWSPAAGKWHVQKVQKQQQPQ 859

  Fly  1201 AGLSIPPVATPT-SQEESITNSGQPVGLLASALNGTANDVLSSDSIPNDPITPGLATALSEMLLH 1264
            ...::|..||.: :|.:|..|:..     :|:........:......:.|...|..:::|.:.
Zfish   860 QSETVPQTATQSQTQSQSSANNNS-----SSSTRYQTRQSVKVHQKDSSPANTGSGSSISSLA-- 917

  Fly  1265 TGVPKLIARPRGALRSDGSQIYPSQAGPVSQKLKENAHKITDYFISVIEDTLSDMATGDQSVLQA 1329
                             |..:.|..:..|:..:.:...|:.|.....:.:..:|::........|
Zfish   918 -----------------GDFLTPPASADVAADIAKYTTKMMDVIKGTMTEIYNDLSKSTTGNTIA 965

  Fly  1330 RIAGLSLENERLKQHYDRQINDLHRTSELMISEMRKTLEQEHKRVISELRQQNAIELMRAVEEAK 1394
            .|..|.:|.|:|:..:.::::::....||.::|||::||||.:|::||:::|..:|..:||:|.|
Zfish   966 EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERERLVSEVKKQMELEKQQAVDETK 1030

  Fly  1395 RKQWCANCMREAQLYCCWNTSYCDYPCQQLHWPGHSATCGQSV-----------------PPTIP 1442
            :|||||||.:||..|||||||||||||||.|||.|..:|.||.                 .|...
Zfish  1031 KKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATSSQQETEAEASSDAAGKPVGQ 1095

  Fly  1443 VPPSVPTPIIEPGRAKAKVATPTATPSITNPSPSSQI 1479
            .|.:.|.|..|    |...|....:||..|...||.:
Zfish  1096 SPKTQPPPSAE----KTSPANRGPSPSTDNTKSSSSV 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zmynd8	NP_651881.2	PHD_PRKCBP1	345..386	CDD:277013	13/40 (33%)
		Bromo_RACK7	403..501	CDD:99940	34/99 (34%)
		PWWP_PRKCBP1	523..616	CDD:438988	39/92 (42%)
		zf-MYND	1399..1433	CDD:460312	25/33 (76%)
		PHA03247	<1427..1592	CDD:223021	17/70 (24%)
prkcbp1l	NP_955935.3	None