DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek6 and SLITRK6

DIOPT Version :9

Sequence 1:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster
Sequence 2:NP_115605.2 Gene:SLITRK6 / 84189 HGNCID:23503 Length:841 Species:Homo sapiens


Alignment Length:252 Identity:71/252 - (28%)
Similarity:117/252 - (46%) Gaps:27/252 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 SCASNCTCKWTNGKKSAICSS-----LQLTTIPNTLSTELQVLVLNDNHIPYLNREEFSTLGLLN 96
            ||.|.|.|:..:|.....|.:     :...::|.:...:|.:|   :|.:..|:..:||  ||.|
Human    30 SCDSLCNCEEKDGTMLINCEAKGIKMVSEISVPPSRPFQLSLL---NNGLTMLHTNDFS--GLTN 89

  Fly    97 LQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAY 161
            ...|:|..:.:..|...:|..|.:|.::.::.|.||:|.:|||.|.:.|..|..:.|.:..:...
Human    90 AISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITVIEPS 154

  Fly   162 QFPILPHLRTLDMHDCLISYIDPMSLANLNLLEF-----LNLKNNLLESLSEYV--FQHMANLKT 219
            .|..|..|:.|.::|..|..:.|      |:..|     |:|:.|.|::| .||  .:|:..:..
Human   155 AFSKLNRLKVLILNDNAIESLPP------NIFRFVPLTHLDLRGNQLQTL-PYVGFLEHIGRILD 212

  Fly   220 LSLEENPWQCNCKLRKFRGWYVNSRLSSV--SLVCKGPPAQKDRTWDSVDDELFGCP 274
            |.||:|.|.|||.|.:.:.|..|....|:  .:||..||..|......:..|.. ||
Human   213 LQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVVCNSPPFFKGSILSRLKKESI-CP 268

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 8/24 (33%)
LRR_8 96..155 CDD:290566 18/58 (31%)
leucine-rich repeat 97..120 CDD:275380 5/22 (23%)
leucine-rich repeat 121..144 CDD:275380 9/22 (41%)
LRR_4 144..186 CDD:289563 10/41 (24%)
leucine-rich repeat 145..168 CDD:275380 5/22 (23%)
leucine-rich repeat 169..216 CDD:275380 15/53 (28%)
LRRCT 225..274 CDD:214507 15/50 (30%)
Ig 295..367 CDD:143165
SLITRK6NP_115605.2 PLN00113 69..>494 CDD:331614 63/213 (30%)
leucine-rich repeat 69..89 CDD:275380 8/24 (33%)
LRR 1 89..110 5/20 (25%)
LRR_8 92..146 CDD:316378 16/53 (30%)
leucine-rich repeat 94..113 CDD:275380 4/18 (22%)
LRR 2 113..134 8/20 (40%)
leucine-rich repeat 114..137 CDD:275380 9/22 (41%)
LRR_8 137..195 CDD:316378 15/63 (24%)
LRR 3 137..158 4/20 (20%)
leucine-rich repeat 138..161 CDD:275380 5/22 (23%)
LRR 4 161..182 6/26 (23%)
leucine-rich repeat 162..177 CDD:275380 4/14 (29%)
LRR 5 184..205 7/21 (33%)
leucine-rich repeat 185..260 CDD:275380 25/75 (33%)
leucine-rich repeat 261..412 CDD:275380 3/9 (33%)
LRR 6 364..385
leucine-rich repeat 366..388 CDD:275380
LRR 7 388..409
LRR_8 411..471 CDD:316378
LRR 8 412..433
leucine-rich repeat 413..436 CDD:275380
LRR 9 436..457
leucine-rich repeat 437..460 CDD:275380
LRR_8 459..518 CDD:316378
LRR 10 460..481
leucine-rich repeat 461..482 CDD:275380
LRR 11 483..504
LRRCT 517..567 CDD:214507
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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