Protein Alignment kek6 and lrrn3

DIOPT Version :10

• Sequence 1: NP_001263151.1
• Gene: kek6 / 43729
• FlyBaseID: FBgn0039862
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001072526.1
• Gene: lrrn3 / 779981
• XenbaseID: XB-GENE-490955
• Length: 706
• Species: Xenopus tropicalis
• Alignment Length: 529
• Identity: 106/529 - (20%)
• Similarity: 187/529 - (35%)
• Gaps: 192/529 - (36%)

  Fly    36 LSCASNCTCK---WTNGKKSAI------CSSLQLTTIPNTLSTELQVLVL---------NDNHIP 82
            :.|..:|:|:   |...|...|      |::|.|.::|:.|..:.|:|:|         |.:|.|
 Frog    27 MDCPHSCSCEIRPWFTPKSIYIEALTVDCNALDLYSVPDKLPAKTQILLLQANNIEEIKNTDHFP 91

  Fly    83 ------------------------------YLNREEFSTL------GLLNLQRIYLKKSEVQYIH 111
                                          ||...:.:.|      ||.|||.:|:..:.:..|.
 Frog    92 VNLTGLDLSQNNLSLIANINFTNMHQILSVYLEENKLTELMEGSFSGLENLQELYINHNLISVIS 156

  Fly   112 KESFRNLKILVEIDLSDNKLEMLDK---------------------------------------- 136
            .::|..:..|:.:.|:.|:|:|::.
 Frog   157 PKAFAGVSNLLRLHLNSNRLQMINSMWFEAIPNLEILMIGENPIVNIEDMNFKPLINLRSLVLAG 221

  Fly   137 --------DTFMGNDR------------------------LRILYLNGNPLKRLAAYQFPILPHL 169
                    :.|:|.|:                        |:.|.||.||::|:....|..:.||
 Frog   222 VNLTEIPDNAFLGLDKLESISFYDNKFIHVPSVALQKVVNLKFLDLNKNPVRRIQRGDFSNMLHL 286

  Fly   170 RTLDMH--------DCL------------------ISYIDPMSLANLNLLEFLNLKNNLLESLSE 208
            :.|.::        |.|                  ::||.|.:...|..||.|.|.:|.|.::..
 Frog   287 KELGINNMPELVSIDSLAIENLPELRKIEATNNPKLAYIHPNAFYRLPKLETLMLNSNSLSAIYR 351

  Fly   209 YVFQHMANLKTLSLEENPWQCNCKLRKFRGWYVNSRLSSV------SLVCKGPPAQKDRTWDSVD 267
            ...:.:.|||.:|:..||.:|:|.:|     ::|...:|:      ||.|..||..:......|.
 Frog   352 STIEALPNLKEISIHSNPMRCDCVIR-----WINMNKTSIRFMEPDSLFCFDPPEFQGLNIRQVH 411

  Fly   268 --DELFGCPPRVEIFNNEEVQNIDIGSNTTFSCLVYGDPLPEVAW--ELNGKILDNDNVLFESES 328
              :.:..|.|.:...:.....:::.||:.:..|....:|.||:.|  ....|::.|
 Frog   412 FREMMEICLPLIAPQSFPLDLDLNTGSSVSLHCRATAEPEPEIYWITPSGYKLVPN--------- 467

  Fly   329 IASDKLW----SNLTVFNVTSLDAGTYACTGSNSI------------GSMTQNISIYLSEIVQHV 377
            |||...:    ..||:.||:..:||.|.|...|.:            ||.|..::..|..|::.|
 Frog   468 IASGIFYVHPEGTLTIKNVSLAEAGLYTCVAKNLVGADLKTILITVDGSFTGEVNGSLKIIIKEV 532

  Fly   378 LEKTPETFW 386
            ...:....|
 Frog   533 QSNSVMVSW 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek6	NP_001263151.1	LRR	<56..>226	CDD:443914	56/312 (18%)
		leucine-rich repeat	71..96	CDD:275380	11/69 (16%)
		LRR_8	96..155	CDD:404697	19/130 (15%)
		leucine-rich repeat	97..120	CDD:275380	5/22 (23%)
		leucine-rich repeat	121..144	CDD:275380	7/70 (10%)
		leucine-rich repeat	145..168	CDD:275380	8/22 (36%)
		leucine-rich repeat	169..216	CDD:275380	14/72 (19%)
		LRRCT	225..274	CDD:214507	13/56 (23%)
		Ig	286..360	CDD:472250	21/91 (23%)
		Ig strand B	294..298	CDD:409353	0/3 (0%)
		Ig strand C	307..310	CDD:409353	1/2 (50%)
		Ig strand E	336..340	CDD:409353	1/3 (33%)
		Ig strand F	350..355	CDD:409353	2/4 (50%)
lrrn3	NP_001072526.1	LRRNT	28..72	CDD:214470	11/43 (26%)
		leucine-rich repeat	52..70	CDD:275380	5/17 (29%)
		leucine-rich repeat	71..93	CDD:275380	6/21 (29%)
		LRR	73..>369	CDD:443914	51/295 (17%)
		leucine-rich repeat	94..117	CDD:275380	0/22 (0%)
		leucine-rich repeat	118..141	CDD:275380	5/22 (23%)
		leucine-rich repeat	142..165	CDD:275380	5/22 (23%)
		leucine-rich repeat	166..189	CDD:275380	5/22 (23%)
		leucine-rich repeat	190..213	CDD:275380	0/22 (0%)
		leucine-rich repeat	214..237	CDD:275380	2/22 (9%)
		leucine-rich repeat	238..261	CDD:275380	0/22 (0%)
		leucine-rich repeat	262..285	CDD:275380	8/22 (36%)
		leucine-rich repeat	286..310	CDD:275380	4/23 (17%)
		leucine-rich repeat	311..333	CDD:275380	3/21 (14%)
		leucine-rich repeat	336..359	CDD:275378	6/22 (27%)
		PCC	341..>407	CDD:188093	19/70 (27%)
		leucine-rich repeat	360..372	CDD:275378	5/11 (45%)
		Ig_3	426..500	CDD:464046	20/82 (24%)