DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek6 and Tril

DIOPT Version :9

Sequence 1:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster
Sequence 2:NP_080093.1 Gene:Tril / 66873 MGIID:1914123 Length:809 Species:Mus musculus


Alignment Length:366 Identity:88/366 - (24%)
Similarity:144/366 - (39%) Gaps:78/366 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    60 LTTIPNTLSTELQVLV---LNDNHIPYLNREEFSTLG------------------------LLNL 97
            |..:|:.:...|..|:   |..|.|.:|.:..||.||                        |.:|
Mouse   167 LGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFSQLGKLRFLNLSANELQPSLRHAATFVPLRSL 231

  Fly    98 QRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAYQ 162
            ..:.|..:.:|::....|::|..|..:.||.|:|..|..:.|.|.:.||.|.|.||.|.:|....
Mouse   232 STLILSANSLQHLGPRVFQHLPRLGLLSLSGNQLTHLAPEAFWGLEALRELRLEGNRLNQLPLTL 296

  Fly   163 FPILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMANLKTLSLEENPW 227
            ...|..|..||:....:|.:.|.:..:...|..|:|::|.|.:||..:|.....|..|.|:.|.|
Mouse   297 LEPLHSLEALDLSGNELSALHPATFGHQGRLRELSLRDNALSALSGDIFAASPALYRLDLDGNGW 361

  Fly   228 QCNCKLRKFR----GWYVNSRLSSVSLVCKGPPAQKDRTWDSVDDELF---GC------------ 273
            .|:|:||..:    .|:...||.:|.:.|:.|||.:.:..|.:||:|.   .|            
Mouse   362 TCDCRLRGLKRWMGNWHSQGRLLTVFVQCRHPPALRGKYLDYLDDQLLQNGSCVDPSPSPTAGSR 426

  Fly   274 ----PPRVEIFNNEEVQNIDIGSNTTFSCLVYGDP------LPEVAWELNGKILDNDNVLFESES 328
                |.     ::||......|.:..........|      ||.|||  .|              
Mouse   427 QWPLPT-----SSEEGMTPPAGLSQELPLQPQPQPQQRGRLLPGVAW--GG-------------- 470

  Fly   329 IASDKLWSNLTVFNVTSLDAGTYACTGSNSIGSMTQNISIY 369
             |:.:|..|.:...::....|.:....:.:.||..|::.::
Mouse   471 -AAKELVGNRSALRLSRRGPGPHQGPSAAAPGSAPQSLDLH 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 11/51 (22%)
LRR_8 96..155 CDD:290566 19/58 (33%)
leucine-rich repeat 97..120 CDD:275380 5/22 (23%)
leucine-rich repeat 121..144 CDD:275380 8/22 (36%)
LRR_4 144..186 CDD:289563 14/41 (34%)
leucine-rich repeat 145..168 CDD:275380 9/22 (41%)
leucine-rich repeat 169..216 CDD:275380 13/46 (28%)
LRRCT 225..274 CDD:214507 19/71 (27%)
Ig 295..367 CDD:143165 14/77 (18%)
TrilNP_080093.1 LRR_RI <11..194 CDD:238064 7/26 (27%)
leucine-rich repeat 37..57 CDD:275378
LRR 1 61..81
LRR_8 84..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..108 CDD:275380
LRR 3 108..129
leucine-rich repeat 109..132 CDD:275380
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275380
LRR_8 156..215 CDD:290566 12/47 (26%)
LRR 5 156..177 2/9 (22%)
leucine-rich repeat 157..180 CDD:275380 3/12 (25%)
LRR 6 180..201 6/20 (30%)
leucine-rich repeat 181..204 CDD:275380 8/22 (36%)
LRR 7 204..223 0/18 (0%)
leucine-rich repeat 205..230 CDD:275380 1/24 (4%)
LRR_RI 229..>364 CDD:238064 40/134 (30%)
LRR_8 229..289 CDD:290566 19/59 (32%)
LRR 8 230..251 4/20 (20%)
leucine-rich repeat 231..254 CDD:275380 5/22 (23%)
LRR 9 254..275 7/20 (35%)
leucine-rich repeat 255..278 CDD:275380 8/22 (36%)
LRR 10 278..298 8/19 (42%)
leucine-rich repeat 279..302 CDD:275380 9/22 (41%)
LRR_8 302..359 CDD:290566 16/56 (29%)
LRR 11 302..323 5/20 (25%)
leucine-rich repeat 303..323 CDD:275380 5/19 (26%)
LRR 12 326..347 8/20 (40%)
leucine-rich repeat 327..350 CDD:275380 8/22 (36%)
TPKR_C2 359..406 CDD:301599 15/46 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 412..462 6/54 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 483..563 4/28 (14%)
FN3 587..659 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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