DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek6 and nyx

DIOPT Version :9

Sequence 1:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster
Sequence 2:NP_001071085.1 Gene:nyx / 568821 ZFINID:ZDB-GENE-061026-3 Length:469 Species:Danio rerio


Alignment Length:515 Identity:116/515 - (22%)
Similarity:171/515 - (33%) Gaps:189/515 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 VCWILLCLVAWTVADDWSLS---CASNC--TCKWTNGKK-SAICSSLQLTTIPNTLSTELQVLVL 76
            :|:|:...|.:.:....:||   |..:|  ||..|..|. |.:|..:.:..:|.....|...:.|
Zfish     1 MCFIINIAVYFLLLPPHALSLWACTRSCPPTCTCTQEKSCSVLCDHVNMMDLPKEFPCEASSINL 65

  Fly    77 NDNHIPYLNREEFSTL----------------------GLLNLQRIYLKKSE-VQYIHKESFRNL 118
            :.|.:.:|:...|.||                      ||.||..:.:..:| ::|:|..:|..|
Zfish    66 DKNSLKFLSERAFGTLPSLKTLSLKYNNISFITPGAFKGLPNLVELKMAHNEYIRYLHTRTFTAL 130

  Fly   119 KILVEIDLSD-----------------------------------------------NKLEM--- 133
            |.||.:||||                                               ||:|.   
Zfish   131 KRLVRLDLSDCNLFNMPDRIFLEQITLKELLCFQNNFRRVPGALRGMENLTHVYLERNKIEAVAY 195

  Fly   134 ---------------------------------------------LDKDTFMGNDRLRILYLNGN 153
                                                         |.:..|.|...|::|.|.||
Zfish   196 NSLLGLTSLKYLNLQENRINVIHDEAFKDLIRLENFYLNDNLLVDLPQQAFKGLSNLKMLNLGGN 260

  Fly   154 PLKRLAAYQFPILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMANLK 218
            .|..::...|..|..|..|.:....:|||:..|..||..|..|:|.:|.|.||...|||.:..:.
Zfish   261 LLTNVSKTWFSDLVELEVLYLDRNRLSYIEDGSFENLTSLITLHLNSNNLTSLPFSVFQPIYFIG 325

  Fly   219 TLSLEENPWQCNCKLRKFRGWYVNSRLSSVSLVCKGPPAQKDRTWDSVDDELFGCPPRVEIFNNE 283
            .|.|..|||:|.|.|...|.|     :.|..||...|.|.               |..|...:..
Zfish   326 RLYLFRNPWECTCDLEWLREW-----MESYKLVRDIPCAS---------------PSSVAGLDLS 370

  Fly   284 EVQNIDIGSNTTFSCLVYGDPLPEVAWELNGKILDNDNVLFESESIASDKLWSNL--TVFNVT-S 345
            ||    :.::...:||   || ||:  .:...:.|...|..:..|:.|..|...|  .:.|:| |
Zfish   371 EV----VFAHLNSTCL---DP-PEL--NMTTSLPDYPTVENKFNSLISKLLQQELRDEMVNITDS 425

  Fly   346 LDAGTYACTGSNSIGSMTQNISIYLSEIVQHVLEKTPETFWYFGLIMGIFG---TVFLLI 402
            |..||......:.:.|             .|                |:||   |||||:
Zfish   426 LRNGTQQDPAESQVSS-------------AH----------------GLFGASQTVFLLV 456

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 8/46 (17%)
LRR_8 96..155 CDD:290566 25/154 (16%)
leucine-rich repeat 97..120 CDD:275380 6/23 (26%)
leucine-rich repeat 121..144 CDD:275380 12/117 (10%)
LRR_4 144..186 CDD:289563 13/41 (32%)
leucine-rich repeat 145..168 CDD:275380 8/22 (36%)
leucine-rich repeat 169..216 CDD:275380 18/46 (39%)
LRRCT 225..274 CDD:214507 13/48 (27%)
Ig 295..367 CDD:143165 19/74 (26%)
nyxNP_001071085.1 leucine-rich repeat 64..83 CDD:275380 6/18 (33%)
LRR_8 82..143 CDD:290566 16/60 (27%)
leucine-rich repeat 84..107 CDD:275380 2/22 (9%)
leucine-rich repeat 108..132 CDD:275380 6/23 (26%)
LRR_RI <127..311 CDD:238064 35/183 (19%)
leucine-rich repeat 133..179 CDD:275380 6/45 (13%)
LRR_8 179..238 CDD:290566 3/58 (5%)
leucine-rich repeat 180..203 CDD:275380 3/22 (14%)
leucine-rich repeat 204..227 CDD:275380 0/22 (0%)
LRR_8 227..286 CDD:290566 13/58 (22%)
leucine-rich repeat 228..251 CDD:275380 3/22 (14%)
leucine-rich repeat 252..275 CDD:275380 8/22 (36%)
LRR_8 275..333 CDD:290566 20/57 (35%)
leucine-rich repeat 276..299 CDD:275380 8/22 (36%)
leucine-rich repeat 300..319 CDD:275380 8/18 (44%)
LRRCT 332..>366 CDD:214507 15/53 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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