Protein Alignment kek6 and lrrc24

DIOPT Version :10

• Sequence 1: NP_001263151.1
• Gene: kek6 / 43729
• FlyBaseID: FBgn0039862
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: XP_009297158.2
• Gene: lrrc24 / 565790
• ZFINID: ZDB-GENE-060503-496
• Length: 692
• Species: Danio rerio
• Alignment Length: 610
• Identity: 147/610 - (24%)
• Similarity: 237/610 - (38%)
• Gaps: 145/610 - (23%)

  Fly    35 SLSCASNCTCKWTNGKKSAICSSLQLTTIPNTLSTELQVLVLNDNHIPYLNREEFSTLGLLNLQR 99
            ||:|.|.|.|.    ..:..|.|:.:..||..::...|.:.|.||.|..:.:.:.|.||  .|..
Zfish   119 SLACPSGCRCY----SLTVECGSIGIKEIPQGITQGTQTIFLQDNAIGQIRQRDLSDLG--QLHY 177

  Fly   100 IYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAYQFP 164
            :||:.:.:..:...:||:|.:|:|:.|:.|::.::..|.|.|.|.||||||.||.:.||..|.|.
Zfish   178 LYLQNNSISTLEPGAFRSLGLLLELALNGNRIHLITADVFRGLDHLRILYLAGNQINRLEDYTFR 242

  Fly   165 ILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMANLKTLSLEENPWQC 229
            .|..|:.|.:.:.::..:...:|..|:.|..|:|..|.|.:||....:.:.:|:.|.:.:|||:|
Zfish   243 GLQRLQELHLQENVLEVLGDQALVGLSSLALLDLSRNNLRTLSPASLKPLVSLQVLRVTDNPWRC 307

  Fly   230 NCKLRKFRGWYVNSR----LSSVS--LVCKGPPAQKDRTWDSVDDELFGC-PPRVEIFNNEEVQN 287
            :|.|...||| :|..    |||..  ::|..||.....:...|......| ||.|::  ......
Zfish   308 DCALHWLRGW-INEEGQRLLSSAERRMLCAEPPRLSHLSLVEVPPNSLVCIPPVVQL--EPSHLT 369

  Fly   288 IDIGSNTTFSCLVYGDPLPEVAWE--LNGKI------------LDND------------------ 320
            :.:|.:...||...|.|.|:|.|.  .:||.            :|.|
Zfish   370 VRLGESLRVSCQASGYPQPQVTWRKASHGKAQLSPRGLVQEVGMDGDTRNGGRLVTARPGGKGGP 434

  Fly   321 ----------NVLFESESIASDKLWSNLTVFNVTSLDAGTYACTGSN--SIGSMTQNISIYLSEI 373
                      :...:.|:...|.....|.:.|||...||.|.|...|  .:..:|.::|:.:|.
Zfish   435 SSHGPIRGGADDGADRENFDPDTGSGMLFLSNVTVAHAGRYECEAWNPGGVARVTFHLSVNMSS- 498

  Fly   374 VQHVLEKTPETFW-------YF----------------GLIMGIFGTV--------FLLISISFV 407
                 ..:....|       |:                .:.....||.        ..|::::.:
Zfish   499 -----SSSRSEIWPRLHSSSYYHPSSVDVSQEPLYELESMDFNALGTATQTAIAVGISLLALTAL 558

  Fly   408 VCLCKRTTRQHRHANK--AGVKSSVSFNDQEKKLLDSSVTTTTNDRGDSYGIDNQPTSIGMNKGD 470
            :.||...:| ||...|  .|..:|     :|:.:|      ..||..|.      ||:
Zfish   559 LLLCMIYSR-HRQRQKEEGGYGAS-----KEESIL------YVNDYSDG------PTT------- 598

  Fly   471 SAGMGFNQIEIHAVESHRHGSMLVQQQ------PQQQQVAGGGGMRQQLMQVKDSTCGMMSVPTS 529
                 |.|:|.:..|  |...|.|..:      ||...:..|..      .:|.|.|..:..|..
Zfish   599 -----FAQLEEYRDE--RGHEMYVLNRAKPVLAPQPMCIQQGSA------TLKASECQGVLTPGR 650

  Fly   530 MAG-HAHSHPAQISEEFPLN-VGVF 552
            ..| .....||:..|..||: .|:|
Zfish   651 AGGIGPRRAPAEGGEAPPLDPEGLF 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek6	NP_001263151.1	LRR	<56..>226	CDD:443914	51/169 (30%)
		leucine-rich repeat	71..96	CDD:275380	8/24 (33%)
		LRR_8	96..155	CDD:404697	22/58 (38%)
		leucine-rich repeat	97..120	CDD:275380	6/22 (27%)
		leucine-rich repeat	121..144	CDD:275380	7/22 (32%)
		leucine-rich repeat	145..168	CDD:275380	13/22 (59%)
		leucine-rich repeat	169..216	CDD:275380	11/46 (24%)
		LRRCT	225..274	CDD:214507	18/55 (33%)
		Ig	286..360	CDD:472250	23/117 (20%)
		Ig strand B	294..298	CDD:409353	0/3 (0%)
		Ig strand C	307..310	CDD:409353	1/2 (50%)
		Ig strand E	336..340	CDD:409353	1/3 (33%)
		Ig strand F	350..355	CDD:409353	2/4 (50%)
lrrc24	XP_009297158.2	None