DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek6 and Rtn4rl2

DIOPT Version :9

Sequence 1:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster
Sequence 2:XP_006499655.1 Gene:Rtn4rl2 / 269295 MGIID:2669796 Length:480 Species:Mus musculus


Alignment Length:307 Identity:83/307 - (27%)
Similarity:126/307 - (41%) Gaps:60/307 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 CWILLCLVAWTVADDWSLSCASNCTCKWTNGKKSAICSSLQLTTIPNTLSTELQVLVLNDNHIPY 83
            |.:|..|...:|..    ||...|||  .:...:..|.:...:::|.:|....|.|.|.:|.|..
Mouse    76 CLLLTLLALPSVTP----SCPMLCTC--YSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLIRS 134

  Fly    84 LNREEFSTLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNK-LEMLDKDTFMGNDRLRI 147
            |....|..    ||..::|..:.:..||..:||:|:.|.|:||.||: |..|:.|||.|.:||:.
Mouse   135 LRPGTFGP----NLLTLWLFSNNLSTIHPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQS 195

  Fly   148 ------------------------------------------------LYLNGNPLKRLAAYQFP 164
                                                            |:|:||.|:.|..:.|.
Mouse   196 LHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFR 260

  Fly   165 ILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMANLKTLSLEENPWQC 229
            .|..|..|.:|...:..:...:...|:.|..|.|.||.|.||.......:..|:.|.|..|||.|
Mouse   261 GLGSLDRLLLHGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLPALEFLRLNANPWAC 325

  Fly   230 NCKLRKFRGWYVNSRLSSVSLVCKGPPAQKDRTWDSVDDELF-GCPP 275
            :|:.|....|:..:|:||..:.|..||.::.|...::.|..| .|||
Mouse   326 DCRARPLWAWFQRARVSSSDVTCATPPERQGRDLRALRDSDFQACPP 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 7/24 (29%)
LRR_8 96..155 CDD:290566 26/107 (24%)
leucine-rich repeat 97..120 CDD:275380 7/22 (32%)
leucine-rich repeat 121..144 CDD:275380 12/23 (52%)
LRR_4 144..186 CDD:289563 13/89 (15%)
leucine-rich repeat 145..168 CDD:275380 9/70 (13%)
leucine-rich repeat 169..216 CDD:275380 12/46 (26%)
LRRCT 225..274 CDD:214507 16/49 (33%)
Ig 295..367 CDD:143165
Rtn4rl2XP_006499655.1 leucine-rich repeat 122..143 CDD:275380 7/24 (29%)
LRR_8 143..203 CDD:338972 22/59 (37%)
leucine-rich repeat 144..167 CDD:275380 7/22 (32%)
leucine-rich repeat 168..192 CDD:275380 12/23 (52%)
leucine-rich repeat 193..216 CDD:275380 1/22 (5%)
LRR_8 216..275 CDD:338972 11/58 (19%)
leucine-rich repeat 217..240 CDD:275380 0/22 (0%)
leucine-rich repeat 241..264 CDD:275380 8/22 (36%)
LRR_8 264..322 CDD:338972 15/57 (26%)
leucine-rich repeat 265..288 CDD:275380 4/22 (18%)
leucine-rich repeat 289..312 CDD:275380 8/22 (36%)
LRRCT 321..371 CDD:214507 16/49 (33%)
PHA03247 349..>429 CDD:223021 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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