DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek6 and Slitrk6

DIOPT Version :9

Sequence 1:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster
Sequence 2:NP_780708.1 Gene:Slitrk6 / 239250 MGIID:2443198 Length:840 Species:Mus musculus


Alignment Length:436 Identity:100/436 - (22%)
Similarity:173/436 - (39%) Gaps:84/436 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 SCASNCTCKWTNGKKSAIC-----SSLQLTTIPNTLSTELQVLVLNDNHIPYLNREEFSTLGLLN 96
            ||.:.|.|:..:|.....|     :.|...::|.:....|.:|   :|.:..|:..:||  ||.|
Mouse    30 SCDTLCNCEEKDGIMIINCEEKGINKLSQISVPPSRPFHLSLL---NNGLTMLHTNDFS--GLTN 89

  Fly    97 LQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAY 161
            ...|:|..:.:..|...:|..|.:|.::.::.|.||:|.:|||.|.:.|..|..:.|.:..:...
Mouse    90 ALSIHLGFNNIADIETGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFLQADNNFITIIEPS 154

  Fly   162 QFPILPHLRTLDMHDCLISYIDPMSLANLNLLEF-----LNLKNNLLESLSEYV--FQHMANLKT 219
            .|..|..|:.|.::|..|..:.|      |:..|     |:|:.|.|::| .||  .:|:..:..
Mouse   155 AFSKLNRLKVLILNDNAIESLPP------NIFRFVPLTHLDLRGNQLQTL-PYVGFLEHIGRILD 212

  Fly   220 LSLEENPWQCNCKLRKFRGWYVNSRLSSV--SLVCKGPPAQKDRTWDSVDDELFGC--PPRVEIF 280
            |.||:|.|.|||:|.:.:.|..|....|:  .::|..||..|......:..|.| |  ||..|..
Mouse   213 LQLEDNKWACNCELLQLKNWLENMPPQSIIGDVICYSPPPFKGSVLSRLKKESF-CPTPPVYEEH 276

  Fly   281 NNEEVQNIDIGSNTTFSCLVYGD------------------------PLPEVAWELNGKILDNDN 321
            .:.....:.|.|:|:.|.|...:                        |:|......|.|:|....
Mouse   277 EDPSGSLLAITSSTSDSRLSSKNTSILKQPTKAPGLIPYLTKPSTQLPVPYCPIPCNCKVLSPSG 341

  Fly   322 VLFESE------------------------SIASDKLWSNLT-VFNVTSLDAGTYACTGSNSIGS 361
            :|...:                        :|....:.|:|| .|.:..|.      .|:|.|..
Mouse   342 LLIHCQERNIESLSDLQPPPHNPRKLILAGNIIHTLMKSDLTDYFTLEMLH------LGNNRIEV 400

  Fly   362 MTQNISIYLSEIVQHVLEKTPETFWYFGLIMGIFGTVFLLISISFV 407
            :.:...:.|:.:.:..|.....|....|:.:|:....:|.:..:.|
Mouse   401 LEEGSFMNLTRLQKLYLNGNHLTKLNKGMFLGLHSLEYLYLEYNAV 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 8/24 (33%)
LRR_8 96..155 CDD:290566 18/58 (31%)
leucine-rich repeat 97..120 CDD:275380 5/22 (23%)
leucine-rich repeat 121..144 CDD:275380 9/22 (41%)
LRR_4 144..186 CDD:289563 10/41 (24%)
leucine-rich repeat 145..168 CDD:275380 5/22 (23%)
leucine-rich repeat 169..216 CDD:275380 15/53 (28%)
LRRCT 225..274 CDD:214507 16/52 (31%)
Ig 295..367 CDD:143165 17/120 (14%)
Slitrk6NP_780708.1 leucine-rich repeat 68..89 CDD:275380 8/25 (32%)
LRR_8 69..124 CDD:290566 16/59 (27%)
LRR 1 89..110 5/20 (25%)
leucine-rich repeat 94..113 CDD:275380 4/18 (22%)
LRR 2 113..134 8/20 (40%)
LRR_8 114..172 CDD:290566 17/57 (30%)
leucine-rich repeat 114..137 CDD:275380 9/22 (41%)
LRR 3 137..158 4/20 (20%)
leucine-rich repeat 138..161 CDD:275380 5/22 (23%)
LRR_8 161..219 CDD:290566 18/64 (28%)
LRR 4 161..182 6/26 (23%)
leucine-rich repeat 162..177 CDD:275380 4/14 (29%)
LRR 5 184..205 7/21 (33%)
leucine-rich repeat 185..260 CDD:275380 24/75 (32%)
leucine-rich repeat 210..222 CDD:275378 5/11 (45%)
TPKR_C2 218..268 CDD:301599 15/50 (30%)
leucine-rich repeat 261..411 CDD:275380 27/156 (17%)
LRR 6 363..384 3/20 (15%)
leucine-rich repeat 365..387 CDD:275380 4/21 (19%)
LRR_8 387..444 CDD:290566 10/62 (16%)
LRR 7 387..408 4/26 (15%)
LRR_4 388..426 CDD:289563 7/43 (16%)
LRR_4 410..449 CDD:289563 6/37 (16%)
LRR 8 411..432 3/20 (15%)
leucine-rich repeat 412..435 CDD:275380 4/22 (18%)
LRR_8 435..493 CDD:290566 2/12 (17%)
LRR 9 435..456 2/12 (17%)
leucine-rich repeat 436..459 CDD:275380 2/11 (18%)
LRR 10 459..480
leucine-rich repeat 460..481 CDD:275380
LRR 11 482..503
LRRCT 516..566 CDD:214507
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 717..736
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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