Protein Alignment kek6 and iglr-3

DIOPT Version :9

• Sequence 1: NP_001263151.1
• Gene: kek6 / 43729
• FlyBaseID: FBgn0039862
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001293349.1
• Gene: iglr-3 / 171771
• WormBaseID: WBGene00021353
• Length: 488
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 118/495 - (23%)
• Similarity: 190/495 - (38%)
• Gaps: 95/495 - (19%)

  Fly    36 LSCASNC--TCK--WTNGKKSAICSSLQL----TTIPNTLSTELQVLVLNDNHIPYLNR--EEFS 90
            :|| ||.  |||  |.:.:.|..|:||.|    ..:||.||     |.|::|.|..:..  .|:.
 Worm    14 ISC-SNAPKTCKSFWISNRPSQDCASLTLQEPPQLLPNVLS-----LSLSNNSIFRITTFPSEYR 72

  Fly    91 TLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPL 155
            .|..|.|.:..|:|.:...:  ..|..|:   |:|:|.|.|..|.....:.:  ||:|.|..|
 Worm    73 RLQSLRLDQCQLEKLDFDAL--SVFEQLR---ELDVSRNSLSKLIIPRNLAS--LRVLNLAFN-- 128

  Fly   156 KRLAAYQF-PILPHLRTLDM----HDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMA 215
                |:.: |.:.||.:|.:    |:.|||....|...|   ||.:.|..|..:.||.:.|.|
 Worm   129 ----AFTYVPDMSHLESLRLVDLSHNRLISVRPRMLPFN---LEVVRLAANRFQHLSPWPFLH-- 184

  Fly   216 NLKTLSLEENPWQCNCKLRKFRGWYVNSRL-SSVSLVCKGPPAQKDRTWDSVDDELFGCPPRVEI 279
            .|:.|.:..|..:|:|.|..|..|.....| .|..|.|:.|...:.   ..:|.:.. |.|.| :
 Worm   185 KLQELDVTFNDLECDCSLWHFVTWAEKLALFDSTMLPCRRPSELRK---SPIDGKTV-CGPTV-V 244

  Fly   280 FNNEEVQNIDIGSNTTFSCLVYGDPLPEVAWELNGKILDNDNVLFESESIASDKLWSNLTVFNVT 344
            .::.|...:.:.......|.....|.|::.|:.|||.:.:.  |.:.....|.||...|.:..|.
 Worm   245 TSSPESAVVSLDDAHVMCCTALATPSPQLYWQFNGKNISSG--LSQKHLSESGKLEFCLEIPKVR 307

  Fly   345 SLDAGTYACTGSNSIGSMTQNISIYLSEIVQHVLEKTPETFWYFGLIMGIFGTVFLLISISFVVC 409
            ..|.|.|.|..  |:..:..:...::......::..:.|     |:::....|:...|.:..|:.
 Worm   308 LKDMGKYKCVA--SLAGLNSSKEFHVERDKIPIVLNSAE-----GIMIYCQFTICTFIGVCCVIS 365

  Fly   410 LC-----------KRTTRQHRHANKAGV-KSSVSFNDQEKKLLDSSVTTTTNDRGDSYGIDNQPT 462
            .|           .|..|::.|.....: ..|..:.:.:    |..|..|..|.||:
 Worm   366 CCVLRTGGGGRGKTRPNREYLHTKVLEIPHDSCEYCEVD----DDDVDDTCEDWGDA-------- 418

  Fly   463 SIGMNKGDSAGMGFNQIEIHAVESHRHGSMLVQQQPQQQQ 502
                             |..||..:.....:..||.|.|:
 Worm   419 -----------------ETAAVRQYLQWRQMQMQQEQMQK 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek6	NP_001263151.1	leucine-rich repeat	71..96	CDD:275380	6/26 (23%)
		LRR_8	96..155	CDD:290566	16/58 (28%)
		leucine-rich repeat	97..120	CDD:275380	5/22 (23%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR_4	144..186	CDD:289563	14/46 (30%)
		leucine-rich repeat	145..168	CDD:275380	7/23 (30%)
		leucine-rich repeat	169..216	CDD:275380	16/50 (32%)
		LRRCT	225..274	CDD:214507	12/49 (24%)
		Ig	295..367	CDD:143165	18/71 (25%)
iglr-3	NP_001293349.1	LRR	<47..>196	CDD:227223	49/171 (29%)
		leucine-rich repeat	51..73	CDD:275380	7/26 (27%)
		leucine-rich repeat	74..97	CDD:275380	6/24 (25%)
		leucine-rich repeat	98..119	CDD:275380	7/23 (30%)
		leucine-rich repeat	120..141	CDD:275380	9/26 (35%)
		leucine-rich repeat	142..163	CDD:275380	6/20 (30%)
		leucine-rich repeat	164..185	CDD:275380	8/22 (36%)
		Ig_3	243..319	CDD:372822	19/80 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870