Protein Alignment kek6 and SLITRK1

DIOPT Version :9

• Sequence 1: NP_001263151.1
• Gene: kek6 / 43729
• FlyBaseID: FBgn0039862
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: NP_001268432.1
• Gene: SLITRK1 / 114798
• HGNCID: 20297
• Length: 696
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 74/287 - (25%)
• Similarity: 127/287 - (44%)
• Gaps: 35/287 - (12%)

  Fly    20 WIL-----LCLVAWTVADDWSLSCASN-CTCKWTNGKKSAIC-----SSLQLTTIPNTLSTELQV 73
            |||     ||..|..|..|   .|... |:|....|.....|     :|||..|.|   :::...
Human     4 WILLLETSLCFAAGNVTGD---VCKEKICSCNEIEGDLHVDCEKKGFTSLQRFTAP---TSQFYH 62

  Fly    74 LVLNDNHIPYLNREEFSTLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDT 138
            |.|:.|.:..|...||:  ...|...::::.:.:..|...:|..|:::..:.:::||::...|.|
Human    63 LFLHGNSLTRLFPNEFA--NFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQT 125

  Fly   139 FMGNDRLRILYLNGNPLKRLAAYQFPILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLL 203
            |:|.|.|..|..:.|.|:.:....|..|..|..|.::|.|||.: |.::.....:..|:|:.|.|
Human   126 FLGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTL-PANVFQYVPITHLDLRGNRL 189

  Fly   204 ESLS-EYVFQHMANLKTLSLEENPWQCNCKLRKFRGWYVNSRLSSV--SLVCKGPPAQKDRTWDS 265
            ::|. |.|.:.:..:..:.||:|||.|.|.|...:.|..|...:::  .:||:.|...:.:..:.
Human   190 KTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALIGRVVCEAPTRLQGKDLNE 254

  Fly   266 ------------VDDELFGCPPRVEIF 280
                        ||..|...|.:.|.|
Human   255 TTEQDLCPLKNRVDSSLPAPPAQEETF 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek6	NP_001263151.1	leucine-rich repeat	71..96	CDD:275380	6/24 (25%)
		LRR_8	96..155	CDD:290566	14/58 (24%)
		leucine-rich repeat	97..120	CDD:275380	3/22 (14%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR_4	144..186	CDD:289563	13/41 (32%)
		leucine-rich repeat	145..168	CDD:275380	6/22 (27%)
		leucine-rich repeat	169..216	CDD:275380	14/47 (30%)
		LRRCT	225..274	CDD:214507	14/62 (23%)
		Ig	295..367	CDD:143165
SLITRK1	NP_001268432.1	leucine-rich repeat	62..83	CDD:275380	6/22 (27%)
		leucine-rich repeat	86..107	CDD:275380	3/20 (15%)
		LRR_8	108..166	CDD:290566	16/57 (28%)
		leucine-rich repeat	108..131	CDD:275380	6/22 (27%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		LRR_8	155..213	CDD:290566	16/58 (28%)
		leucine-rich repeat	156..171	CDD:275380	6/15 (40%)
		leucine-rich repeat	179..237	CDD:275380	17/57 (30%)
		TPKR_C2	212..>250	CDD:301599	11/37 (30%)
		leucine-rich repeat	356..372	CDD:275380
		LRR_8	375..435	CDD:290566
		leucine-rich repeat	377..400	CDD:275380
		leucine-rich repeat	401..424	CDD:275380
		LRR_8	425..483	CDD:290566
		leucine-rich repeat	425..448	CDD:275380
		leucine-rich repeat	449..472	CDD:275380
		LRR_8	471..530	CDD:290566
		leucine-rich repeat	473..495	CDD:275380
		leucine-rich repeat	496..520	CDD:275380
		TPKR_C2	529..579	CDD:301599

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000