Protein Alignment kek6 and lrrc4

DIOPT Version :9

• Sequence 1: NP_001263151.1
• Gene: kek6 / 43729
• FlyBaseID: FBgn0039862
• Length: 843
• Species: Drosophila melanogaster
• Sequence 2: XP_002939414.1
• Gene: lrrc4 / 100493671
• XenbaseID: XB-GENE-968937
• Length: 641
• Species: Xenopus tropicalis
• Alignment Length: 432
• Identity: 99/432 - (22%)
• Similarity: 160/432 - (37%)
• Gaps: 99/432 - (22%)

  Fly    21 ILLCLVAWTVADDWS--LSCASNCTCKWTNGKKSAICSSLQLTTIPNTLSTELQVLVLNDNHIPY 83
            |.|.:..|.....:|  .||.|.|:|  :|.....:|:...|:.:|..:.:..:.|.|.:|:|..
 Frog    21 IYLMVHMWISCAAYSGPQSCPSVCSC--SNQFSKVVCTRRGLSEVPQGIPSNTRSLNLMENNIQM 83

  Fly    84 LNREEFSTLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRIL 148
            :..:.|..|.  :|:.:.|.::.::.|...:|..|..|..::|.||.|.::....|....:||.|
 Frog    84 IQADTFRHLH--HLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLREL 146

  Fly   149 YLNGNPLKRLAAYQFPILPHLRTLDMHDC-LISYIDP------MSLANLNL-------------- 192
            :|..||::.:.:|.|..:|.|..||:.:. .:.||..      .:|..|||
 Frog   147 WLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLYNLKYLNLGMCNIRDMPNLTPL 211

  Fly   193 -----LEF---------------------------------------------LNLKNNLLESLS 207
                 ||.                                             |||.:|.:.||.
 Frog   212 VGLEELEISGNNFPEIKPGSFHGLRSLKKLWIMNSQINTIERNAFDDLTSLVELNLAHNNVTSLP 276

  Fly   208 EYVFQHMANLKTLSLEENPWQCNCKLRKFRGWYVNSRLSSVSLV---CKGPPAQKDRTWDSVDDE 269
            ..:|..:..|..|.|..|||.|:|.: .:..|::...:.:.|..   |..||..:.:....||..
 Frog   277 HDLFAPLKYLVELHLHHNPWDCDCDV-LWLSWWLREYIPTNSTCCGRCHSPPHMRGKYVVEVDHS 340

  Fly   270 LFGCPPRVEIFNNEEVQNIDIGSNTTFSCLVYGDPLPEVAWELNGKILDNDNVLFESE-----SI 329
            :|.|.... |.:.....||..|......|..  ..:..|.|     :|.|..||..:.     :|
 Frog   341 MFQCSAPF-IMDAPRDLNISEGRMAELKCRT--SAMSSVRW-----LLPNGTVLTHASNHPRITI 397

  Fly   330 ASDKLWSNLTVFNVTSLDAGTYACTGSNSIGSMTQNISIYLS 371
            .:|   ..|....|...|.|.|.|..:|..|:  .|.|.||:
 Frog   398 LND---GTLNFSQVLLTDTGVYTCMVTNVAGN--SNASAYLN 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek6	NP_001263151.1	leucine-rich repeat	71..96	CDD:275380	6/24 (25%)
		LRR_8	96..155	CDD:290566	16/58 (28%)
		leucine-rich repeat	97..120	CDD:275380	5/22 (23%)
		leucine-rich repeat	121..144	CDD:275380	6/22 (27%)
		LRR_4	144..186	CDD:289563	14/48 (29%)
		leucine-rich repeat	145..168	CDD:275380	8/22 (36%)
		leucine-rich repeat	169..216	CDD:275380	18/117 (15%)
		LRRCT	225..274	CDD:214507	13/51 (25%)
		Ig	295..367	CDD:143165	18/76 (24%)
lrrc4	XP_002939414.1	LRRNT	40..71	CDD:214470	8/32 (25%)
		LRR	<68..285	CDD:227223	44/218 (20%)
		leucine-rich repeat	71..94	CDD:275380	6/24 (25%)
		leucine-rich repeat	95..118	CDD:275380	5/22 (23%)
		leucine-rich repeat	119..142	CDD:275380	6/22 (27%)
		leucine-rich repeat	143..166	CDD:275380	8/22 (36%)
		leucine-rich repeat	167..191	CDD:275380	5/23 (22%)
		leucine-rich repeat	192..213	CDD:275380	4/20 (20%)
		leucine-rich repeat	214..237	CDD:275380	2/22 (9%)
		leucine-rich repeat	238..261	CDD:275380	0/22 (0%)
		leucine-rich repeat	262..283	CDD:275380	7/20 (35%)
		LRRCT	294..345	CDD:214507	13/51 (25%)
		IG_like	353..435	CDD:214653	24/94 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49155
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910