DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek6 and lrfn2

DIOPT Version :9

Sequence 1:NP_001263151.1 Gene:kek6 / 43729 FlyBaseID:FBgn0039862 Length:843 Species:Drosophila melanogaster
Sequence 2:XP_031758515.1 Gene:lrfn2 / 100491687 XenbaseID:XB-GENE-6035533 Length:765 Species:Xenopus tropicalis


Alignment Length:454 Identity:115/454 - (25%)
Similarity:181/454 - (39%) Gaps:88/454 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 SCASNCTCKWTNGKKSAICSSLQLTTIPNTLSTELQVLVLNDNHIPYLNREEFSTL-GLLNLQRI 100
            ||...|.|:..:.....:|.:..|..:|..:......|.|..|.|..:||::|:.: ||::|.  
 Frog    19 SCPKYCVCQNLSESLGTLCPTKGLLFVPMDIDRRTVELRLGGNFIISINRQDFANMTGLVDLT-- 81

  Fly   101 YLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAYQF-P 164
             |.::.:.||...||.:|:.|..:.|..|:|..|..|.|.|...|:.|.:|.|.|..:|...| .
 Frog    82 -LSRNTISYIQPYSFIDLESLRSLHLDSNRLTNLGDDVFRGLINLQHLIMNNNQLNSIAEDAFED 145

  Fly   165 ILPHLRTLDM-------------------------HDCLISYIDPMSLANLNLLEFLNLKNNLLE 204
            :|..|..||:                         |: ||.||...:..:||.|..|:|.:|.|:
 Frog   146 LLQTLEDLDLSYNNLKTVPWDAVRRMVNLHQLSLDHN-LIYYITEGTFQDLNKLARLDLTSNRLQ 209

  Fly   205 SL-SEYVFQHMANLKT----------LSLEENPWQCNCKLRKFRGWYVNSRLSSVSLVCKGPPAQ 258
            .| .:.:|.......|          ||...||..|||:|.    |............|..|.|.
 Frog   210 KLPPDPIFARSQISMTSATPFSPPLSLSFGGNPLHCNCELL----WLRRLDREDDMETCASPSAL 270

  Fly   259 KDRTWDSVDDELFGC-PPRVEIFNNEEVQNIDI--GSNTTFSCLVYGDPLPEVAWEL-NGKILDN 319
            |.|.:..|.:|.|.| ||.:    .:..|.:.:  |...:..|...|||||.:.|.. :|:::.|
 Frog   271 KGRYFWYVREEEFVCEPPLI----TQYTQRLLVLEGQTASLKCKAVGDPLPVIHWVAPDGRLIGN 331

  Fly   320 DNVLFESESIASDKLWSNLTVFNVTSLDAGTYACTGSNSIGSMTQNISIYLSEIVQHVLEKTPET 384
                 .|.:...|.  ..|.:...||.|.||:.|..:|:.|.:|..:.:.:.:| .||...|..|
 Frog   332 -----SSRTTVYDN--GTLDILITTSKDYGTFTCIAANAAGELTAPVELSIVQI-PHVSNGTGRT 388

  Fly   385 FWYFGLIMGIFGTVFLLISISFVVCLCKRTTRQHRHANKAGVKSSVSFNDQEKKLLDSSVTTTT 448
            ......:..|..:.                     .:|:..||::     .||.::.|.||::|
 Frog   389 APPKSRLSDITSST---------------------KSNRGEVKTA-----PEKAVVVSEVTSST 426

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek6NP_001263151.1 leucine-rich repeat 71..96 CDD:275380 9/25 (36%)
LRR_8 96..155 CDD:290566 19/58 (33%)
leucine-rich repeat 97..120 CDD:275380 7/22 (32%)
leucine-rich repeat 121..144 CDD:275380 8/22 (36%)
LRR_4 144..186 CDD:289563 16/67 (24%)
leucine-rich repeat 145..168 CDD:275380 8/23 (35%)
leucine-rich repeat 169..216 CDD:275380 17/72 (24%)
LRRCT 225..274 CDD:214507 16/49 (33%)
Ig 295..367 CDD:143165 21/72 (29%)
lrfn2XP_031758515.1 LRR_8 51..111 CDD:404697 19/62 (31%)
leucine-rich repeat 53..76 CDD:275380 7/22 (32%)
leucine-rich repeat 77..100 CDD:275380 8/25 (32%)
LRR_8 100..160 CDD:404697 19/59 (32%)
leucine-rich repeat 101..124 CDD:275380 8/22 (36%)
leucine-rich repeat 125..148 CDD:275380 7/22 (32%)
LRR_8 148..208 CDD:404697 14/60 (23%)
leucine-rich repeat 150..173 CDD:275380 3/22 (14%)
leucine-rich repeat 174..197 CDD:275380 6/23 (26%)
LRRCT 241..285 CDD:214507 15/47 (32%)
Ig 288..375 CDD:416386 24/97 (25%)
Ig strand A 288..291 CDD:409353 1/6 (17%)
Ig strand A' 295..298 CDD:409353 1/2 (50%)
Ig strand B 304..312 CDD:409353 1/7 (14%)
Ig strand C 318..323 CDD:409353 1/4 (25%)
Ig strand C' 326..328 CDD:409353 1/1 (100%)
Ig strand D 334..338 CDD:409353 0/3 (0%)
Ig strand E 341..345 CDD:409353 1/3 (33%)
Ig strand F 355..362 CDD:409353 2/6 (33%)
Ig strand G 365..375 CDD:409353 2/9 (22%)
fn3 417..485 CDD:394996 4/10 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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