DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1792 and CG4854

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	95/356 - (26%)
Similarity:	150/356 - (42%)	Gaps:	69/356 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRER 70
            ||.|  .:.....|.:..||:  ...:|:..||:.|...|  :.|..||:.|.|.|:.|:..|..
  Fly    12 CRIC--LVQPKDESLMPTEPD--FPDKIKRCTGVELSESP--DWPNRICTSCALLLRAALKLRSL 70

  Fly    71 VIRTQKTLQE-----------------SPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPE 118
            ..:|:|.|:|                 .....:.:|.::.|.|.:.|::|       |.:|  ..
  Fly    71 CQQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEY-------EYLD--SY 126

  Fly   119 EHLLEETEEPYEICEQNE----QPQVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRL 179
            :..||.:|:  ..|..:|    :|.:..| :|.....|.|  |..|..   .|:.||.
  Fly   127 DVTLESSED--VACSADELVSIEPAISAP-EESVYSLSPK--PVTFED---EDSGQAA------- 176

  Fly   180 TEDEVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQE 244
                           ...|..|...::.......|:..|:..|...|:.|.::|.....|.||..
  Fly   177 ---------------SFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMN 226

  Fly   245 LHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRAF 309
            .|.||..::|.||::.:::.|.||:|:|: |||.:|:.|:.|::||..|..||.|:.:|||.|.|
  Fly   227 THTGNRPYKCDYCDSRFADPSTRIKHQRI-HTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPF 290

  Fly   310 HCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQ 340
            .|..||.||.:..|..||  .|.|..|...:
  Fly   291 SCQYCQKSFSQLHHKNSH--EKSHKRTKEVK 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	22/73 (30%)
		C2H2 Zn finger	198..218	CDD:275368	3/19 (16%)
		C2H2 Zn finger	226..243	CDD:275368	5/16 (31%)
		C2H2 Zn finger	254..275	CDD:275368	8/20 (40%)
		zf-C2H2	281..303	CDD:278523	8/21 (38%)
		C2H2 Zn finger	283..303	CDD:275368	8/19 (42%)
		zf-H2C2_2	296..320	CDD:290200	13/23 (57%)
		C2H2 Zn finger	311..329	CDD:275368	8/17 (47%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	14/50 (28%)
		C2H2 Zn finger	180..200	CDD:275368	3/19 (16%)
		zf-H2C2_2	193..217	CDD:290200	6/23 (26%)
		COG5048	201..>258	CDD:227381	19/57 (33%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		zf-H2C2_2	221..244	CDD:290200	9/22 (41%)
		C2H2 Zn finger	236..256	CDD:275368	8/20 (40%)
		zf-H2C2_2	251..273	CDD:290200	10/22 (45%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		zf-H2C2_2	277..301	CDD:290200	13/23 (57%)
		C2H2 Zn finger	292..312	CDD:275368	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960