DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1792 and CG4424

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	99/373 - (26%)
Similarity:	157/373 - (42%)	Gaps:	85/373 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTC-------GLFIFCSTPSNLFEEPNSVML-HQIEVLTGLFLLGGPGNE-LPPFICSPCELDL 61
            ||||       .:.||.:....|   |..|.| .:||.|:|:.:......| ||..||..|:..|
  Fly    11 CRTCLQDGEAHMVSIFQTADDRL---PGGVSLCDKIESLSGIQIRATAKEEVLPTRICLRCKAFL 72

  Fly    62 QTAIAFRERVIRTQKTLQESPNLGNAELIESFAVGVEKE-IQYAEEVT----EIEVIDLLPEEHL 121
            ..|..||:...|:.:.|:|      ..:.::...||.|| :|.....|    |.|.:: .||:.:
  Fly    73 TLAHKFRQICQRSNEFLRE------YVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLE-PPEDEV 130

  Fly   122 LEE----TEEPYEICEQNEQPQVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTED 182
            |||    ||:|.|     |.|.  .||::::        |||.|.
  Fly   131 LEEGVWSTEDPIE-----ETPH--GPAEKER--------PTVLTV-------------------- 160

  Fly   183 EVV-----------------ALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCS 230
            |::                 |:|.:..    :|..||..:...|....|:.||...:.:.|:.|.
  Fly   161 EMLPAPYPPPASTPPPAPAGAVKGKLH----VCAICGNGYPRKSTLDTHMRRHNDERPYECEICH 221

  Fly   231 QQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGK 295
            :.|:....|:||...|.|...:.|:||:..:::.:..::||| .|.|.:|:.||.|.|.|..:..
  Fly   222 KSFHVNYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHER-THRNERPYACKTCGKKFTYASV 285

  Fly   296 LRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAAL 343
            |:.|..:|||.:...|..|..||.|..:|.:|.:::.|.:.....|.|
  Fly   286 LKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQHINDPRLTAYL 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	26/82 (32%)
		C2H2 Zn finger	198..218	CDD:275368	5/19 (26%)
		C2H2 Zn finger	226..243	CDD:275368	5/16 (31%)
		C2H2 Zn finger	254..275	CDD:275368	6/20 (30%)
		zf-C2H2	281..303	CDD:278523	7/21 (33%)
		C2H2 Zn finger	283..303	CDD:275368	7/19 (37%)
		zf-H2C2_2	296..320	CDD:290200	9/23 (39%)
		C2H2 Zn finger	311..329	CDD:275368	7/17 (41%)
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	27/89 (30%)
		C2H2 Zn finger	189..209	CDD:275368	5/19 (26%)
		DUF45	<204..281	CDD:302795	24/77 (31%)
		COG5048	210..>345	CDD:227381	37/125 (30%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	6/20 (30%)
		zf-H2C2_2	257..282	CDD:290200	11/25 (44%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	9/23 (39%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960