DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1792 and CG31388

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	116/449 - (25%)
Similarity:	169/449 - (37%)	Gaps:	125/449 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRER 70
            ||||......:...|||:..:|.:|.|||.||.|.|  ....:||.|:|..|:.|||.||.||..
  Fly     5 CRTCSRMADPAVAKNLFDPSSSSVLRQIETLTNLQL--KEDGKLPRFMCQDCQHDLQIAIDFRRV 67

  Fly    71 VIRTQKTLQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEEHLLEETEEPYEICEQ- 134
            .|..|            ||:|.....||||.:..|.:.| :.:|..|:|  |.......::.::
  Fly    68 CIEAQ------------ELLELQLRQVEKEEEAFESLAE-QWLDDCPDE--LSNLSPVLQLNDRM 117

  Fly   135 ----NEQPQVKVPAQEKKLRRSTKT--------------TPTVFTSVKFA--------------- 166
                :.:||.|...:...::.:|.|              :|.:.|..:.:
  Fly   118 DFIFDPEPQDKNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPE 182

  Fly   167 ----DNSQATRT--------QWSRLTE----------------------DE----VVALKR---- 189
                ||...:.:        ::..:.|                      ||    ..||.|
  Fly   183 SEAIDNRDTSSSHTCSKCGLEFENVDELKLHKYHLHDIPPDTKFVCDHCDEGFRSAAALTRHCNM 247

  Fly   190 ----------------------ERRKRDC--------ICEQCGRHFTCPSNFKLHLLRHTGVKSF 224
                                  |..|:.|        :|..||:|.|...|.|.||:||.|.:..
  Fly   248 INLPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRH 312

  Fly   225 ACDQCSQQFYTATLLRRHQELHAGNALFQCRY-CEATYSNASGRIQHERMR-HTNVKPFTCKECN 287
            .|||||..||||..|..||:.|.....:.||| |..|:...|.|..|||:. ..:.:.:.|:.|.
  Fly   313 KCDQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCP 377

  Fly   288 KSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAALDNP 346
            ||:....:.|||...|...|...|:.|::||....|..||.:|..|....:...|..:|
  Fly   378 KSYVTPSECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHLKSNAHKTLEARAKAAASP 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	30/73 (41%)
		C2H2 Zn finger	198..218	CDD:275368	9/19 (47%)
		C2H2 Zn finger	226..243	CDD:275368	10/16 (63%)
		C2H2 Zn finger	254..275	CDD:275368	10/22 (45%)
		zf-C2H2	281..303	CDD:278523	7/21 (33%)
		C2H2 Zn finger	283..303	CDD:275368	7/19 (37%)
		zf-H2C2_2	296..320	CDD:290200	9/23 (39%)
		C2H2 Zn finger	311..329	CDD:275368	7/17 (41%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	32/84 (38%)
		C2H2 Zn finger	228..254	CDD:275368	5/25 (20%)
		C2H2 Zn finger	286..306	CDD:275368	9/19 (47%)
		C2H2 Zn finger	314..334	CDD:275368	12/19 (63%)
		C2H2 Zn finger	342..363	CDD:275368	10/20 (50%)
		C2H2 Zn finger	373..393	CDD:275368	7/19 (37%)
		C2H2 Zn finger	401..419	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960