DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1792 and CG8159

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	128/371 - (34%)
Similarity:	183/371 - (49%)	Gaps:	49/371 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CRTCGLFIFCSTPSNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRER 70
            ||.|......|....||......:|.||.:|||:.|...||  ||.::|..|:.||::||:||:|
  Fly     6 CRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPG--LPDWMCETCQTDLKSAISFRDR 68

  Fly    71 VIRTQKTLQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEEHLLEETEEPYEICEQN 135
            .:|:||..:|| .:.|.|  ::|...|.:..:...:..|    |..|     :....|.|:
  Fly    69 CLRSQKIFEES-LVRNEE--DTFRSSVRRSARSQRQRHE----DTAP-----KTPASPLEV---- 117

  Fly   136 EQPQVKVPAQEKKLRRSTKTTPTV--FTSVKFADNSQATRTQWSRLTEDE----VVALKRERRK- 193
               .:|:    :.|....:....:  ..|...||...|.:.. |..|||:    .|.|||.||:
  Fly   118 ---MIKL----ESLSNGDEEDDGIDHLDSCNEADMELAIKAM-SSSTEDDGTTSPVRLKRTRRRG 174

  Fly   194 ---------RDCI------CEQCGRHFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQ 243
                     |..:      |:|||.:.|..|:|..||.:|:|::.|.|:.|..:|.::..|:.||
  Fly   175 LKKGGKGENRTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQ 239

  Fly   244 ELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRA 308
            .:|.|:..||||||:.||.|.|||::||| .|||.:||.|.:|.|||..|..|:.|||.|||.|.
  Fly   240 VMHTGDRKFQCRYCDRTYVNYSGRLRHER-THTNDRPFICAQCGKSFTNSYILKNHMLIHTGERL 303

  Fly   309 FHCDSCQVSFVRRSHLTSHYRSKGHAHTSSAQAALDNPVELDVKAS 354
            |.|:.|..||.|.:||.:|:||..|.|......|....|:|....|
  Fly   304 FRCELCHRSFARPTHLKTHFRSNTHKHNLEKSMADAGGVQLSPSQS 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	29/73 (40%)
		C2H2 Zn finger	198..218	CDD:275368	9/19 (47%)
		C2H2 Zn finger	226..243	CDD:275368	4/16 (25%)
		C2H2 Zn finger	254..275	CDD:275368	13/20 (65%)
		zf-C2H2	281..303	CDD:278523	11/21 (52%)
		C2H2 Zn finger	283..303	CDD:275368	10/19 (53%)
		zf-H2C2_2	296..320	CDD:290200	13/23 (57%)
		C2H2 Zn finger	311..329	CDD:275368	8/17 (47%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	29/73 (40%)
		C2H2 Zn finger	194..214	CDD:275368	9/19 (47%)
		COG5048	<197..322	CDD:227381	60/125 (48%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..270	CDD:275368	13/20 (65%)
		zf-H2C2_2	265..287	CDD:290200	13/22 (59%)
		C2H2 Zn finger	278..298	CDD:275368	10/19 (53%)
		zf-H2C2_2	291..315	CDD:290200	13/23 (57%)
		C2H2 Zn finger	306..328	CDD:275368	10/21 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447760
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.890