DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1792 and CG10959

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster

Alignment Length:	382	Identity:	82/382 - (21%)
Similarity:	150/382 - (39%)	Gaps:	79/382 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRERVIRTQKTLQESPNLGNAELIESFAVGVE 98
            :.:|||..|.....|.......|..:|     :|::..:..:..|.|..: ...||      |:|
  Fly    71 KTVTGLGRLAREEQEFQGVSAEPLAVD-----SFKKEYLPNEDVLSEEED-AEQEL------GLE 123

  Fly    99 KE--------IQYAEEVTEIEVIDLL--PE--------------EHLL-EETEEPYEICEQNEQP 138
            ::        :...::..:.|.||.:  |:              |.|| .|..:.|:..|..|:.
  Fly   124 QDEGNPLRIMVLGGKQSVDEETIDTMWQPDHDSSSASVNEGCALEALLGVENPQDYQPDEDGEEH 188

  Fly   139 QVKVPAQEKKLRRSTKTTPTVFTSVKFADN--------SQATRTQWSRLTEDEVVALKRERRKR- 194
            |.....|.:....:.......:|:.|:.:.        .||.:....:.|.|...||.:.|||.
  Fly   189 QSVFKKQRQPKDYNCPHCDRRYTTQKYLNTHLKMSHPFPQAFKCVDCKATFDVDRALAQHRRKEH 253

  Fly   195 -DCICEQCGRHFTCPSNFKLHLLRHTGVKSFAC--DQCSQQF---YTATLLRR------------ 241
             :..|:.|.:.|....:...|:..|:|.::|.|  :.|.:.|   :..|..||
  Fly   254 TEFACQLCDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCEL 318

  Fly   242 -------------HQELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAMS 293
                         |:..|.|...|||:.|...:::.|...:|:.| |:..||:.|.:|:.:|:..
  Fly   319 CGYRSRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAM-HSTEKPYKCDKCDSAFSRP 382

  Fly   294 GKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRS-KGHAHTSSAQAALDNPVEL 349
            ..|..|...|.|::.|.|..|..::.:.:.|::|.|: |..|..::.:.|...|:|:
  Fly   383 KALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHMRAHKLQASVNATEGAEAEPIEM 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	9/45 (20%)
		C2H2 Zn finger	198..218	CDD:275368	4/19 (21%)
		C2H2 Zn finger	226..243	CDD:275368	6/46 (13%)
		C2H2 Zn finger	254..275	CDD:275368	5/20 (25%)
		zf-C2H2	281..303	CDD:278523	5/21 (24%)
		C2H2 Zn finger	283..303	CDD:275368	5/19 (26%)
		zf-H2C2_2	296..320	CDD:290200	7/23 (30%)
		C2H2 Zn finger	311..329	CDD:275368	4/17 (24%)
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	7/20 (35%)
		COG5048	<258..416	CDD:227381	37/158 (23%)
		C2H2 Zn finger	258..278	CDD:275368	4/19 (21%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	316..336	CDD:275368	1/19 (5%)
		zf-H2C2_2	328..353	CDD:290200	7/24 (29%)
		C2H2 Zn finger	344..364	CDD:275368	5/20 (25%)
		zf-H2C2_2	357..381	CDD:290200	8/24 (33%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		C2H2 Zn finger	400..420	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100