DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1792 and Zfp819

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001014039.1	Gene:	Zfp819 / 308561	RGDID:	1309564	Length:	614	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	76/304 - (25%)
Similarity:	121/304 - (39%)	Gaps:	53/304 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 CSPCELDLQTAI----AFRER---------VIRTQKTLQESPNLGNAELIE------SFAVGVEK 99
            |..|...|.:|:    :..||         |:..:..|::...|...|.:|      :|..|...
  Rat   227 CRLCTQGLSSAVCTTHSTGERACTGNQCANVLSPRSPLRQHGILSQDEPVEYTKDEKAFTAGSAS 291

  Fly   100 EIQYAEEVTEIEV--IDLLPEEHLLEETEEPYEICEQNEQPQVKVPAQEKKLRRSTKTTPTVFTS 162
            ..|......::|.  |..:..:..|:::|..:......|:.:.:.|    ...:|..|:|:...:
  Rat   292 CEQQTTNTLDLETHFICHICGKSFLQKSELSFHPGTSREETRYECP----DCLKSLTTSPSSLQA 352

  Fly   163 VKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQCGRHFTCPSNFKLHLLRHTGVKSFACD 227
            ...|...|...|                       |..||:.|:..|:.|:||..|||.:.:.|.
  Rat   353 HHEAHTKQKPYT-----------------------CHDCGKSFSYASHLKVHLRIHTGERPYVCS 394

  Fly   228 QCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQHERMRHTNVKPFTCKECNKSFAM 292
            .|.:.|...::|..||.:|.|...:.|.:|...:..||...:|.|. ||..||:.|::|.|.|:.
  Rat   395 DCGKAFSQKSVLTTHQRIHTGEKPYACSHCGKLFVYASDLRKHSRF-HTGEKPYECRDCGKVFSN 458

  Fly   293 SGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGHAHT 336
            ...|..|...|||.:.:.|..|..||.|:|||..|    |..||
  Rat   459 KSHLPVHRRIHTGEKPYKCRDCGKSFRRKSHLQVH----GRTHT 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	8/38 (21%)
		C2H2 Zn finger	198..218	CDD:275368	8/19 (42%)
		C2H2 Zn finger	226..243	CDD:275368	4/16 (25%)
		C2H2 Zn finger	254..275	CDD:275368	6/20 (30%)
		zf-C2H2	281..303	CDD:278523	6/21 (29%)
		C2H2 Zn finger	283..303	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..320	CDD:290200	9/23 (39%)
		C2H2 Zn finger	311..329	CDD:275368	9/17 (53%)
Zfp819	NP_001014039.1	KRAB	27..81	CDD:214630
		C2H2 Zn finger	336..357	CDD:275368	4/24 (17%)
		COG5048	<346..538	CDD:227381	54/181 (30%)
		C2H2 Zn finger	365..385	CDD:275368	8/19 (42%)
		C2H2 Zn finger	393..413	CDD:275368	6/19 (32%)
		C2H2 Zn finger	421..441	CDD:275368	6/20 (30%)
		C2H2 Zn finger	449..469	CDD:275368	6/19 (32%)
		C2H2 Zn finger	477..497	CDD:275368	10/23 (43%)
		SFP1	<499..582	CDD:227516	76/304 (25%)
		C2H2 Zn finger	505..525	CDD:275368
		C2H2 Zn finger	533..553	CDD:275368
		C2H2 Zn finger	561..581	CDD:275368
		zf-H2C2_2	573..598	CDD:404364
		C2H2 Zn finger	589..609	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000