DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1792 and znf-782

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	73/282 - (25%)
Similarity:	118/282 - (41%)	Gaps:	45/282 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 TQKTLQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEEHLLEETEEPYEICEQNEQP 138
            |..||.:..::.:.|         |:|.:..|:       :||.||   ||.:|..|..|.::..
Worm    11 TNTTLPDDIHMKDPE---------EEEFEEYED-------ELLEEE---EEFDEELEELENSDSA 56

  Fly   139 QVKVPAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQCGR 203
            ...|.|.......|:..:......::....||.:.:..|...:.|    ||.      ||..||:
Worm    57 SSLVSAGSPHGSSSSNGSHGSSPPLQVQSPSQGSGSSGSPTGQPE----KRH------ICTVCGK 111

  Fly   204 HFTCPSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRI 268
            .|:..|..:.|...|||.|.:.|..|.:.|.....|:.|:..|.|...::|||||.|::....:.
Worm   112 GFSYFSILESHKRSHTGEKPYNCHFCQKTFAQKATLQVHERTHTGERPYKCRYCEKTFAQYGTKT 176

  Fly   269 QHERMRHTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSH------ 327
            .||:..|..::.:.|.:|:|..:....|.||..:| |.:.|.||.|..:|..:::|..|
Worm   177 VHEKSAHLGIRNYKCPKCDKLLSSPSALYTHKKTH-GDKTFRCDFCPKTFALKNYLKLHVKQVHE 240

  Fly   328 ---------YRSKGHAHTSSAQ 340
                     |.:||.|:..|.|
Worm   241 QNERKHVCVYCNKGFAYAGSLQ 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	3/5 (60%)
		C2H2 Zn finger	198..218	CDD:275368	6/19 (32%)
		C2H2 Zn finger	226..243	CDD:275368	4/16 (25%)
		C2H2 Zn finger	254..275	CDD:275368	8/20 (40%)
		zf-C2H2	281..303	CDD:278523	6/21 (29%)
		C2H2 Zn finger	283..303	CDD:275368	6/19 (32%)
		zf-H2C2_2	296..320	CDD:290200	10/23 (43%)
		C2H2 Zn finger	311..329	CDD:275368	6/32 (19%)
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		zf-H2C2_2	119..143	CDD:290200	8/23 (35%)
		C2H2 Zn finger	134..154	CDD:275368	5/19 (26%)
		zf-H2C2_2	147..171	CDD:290200	10/23 (43%)
		C2H2 Zn finger	162..180	CDD:275368	7/17 (41%)
		COG5048	<187..404	CDD:227381	21/77 (27%)
		C2H2 Zn finger	191..211	CDD:275370	6/19 (32%)
		C2H2 Zn finger	218..239	CDD:275368	6/20 (30%)
		C2H2 Zn finger	248..268	CDD:275368	6/15 (40%)
		zf-H2C2_2	260..285	CDD:290200	2/3 (67%)
		C2H2 Zn finger	276..296	CDD:275368
		zf-H2C2_2	288..313	CDD:290200
		C2H2 Zn finger	304..324	CDD:275368
		C2H2 Zn finger	386..403	CDD:275368
		C2H2 Zn finger	424..441	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000