DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1792 and znf1070

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001108190.1	Gene:	znf1070 / 100137121	ZFINID:	ZDB-GENE-080212-4	Length:	363	Species:	Danio rerio

Alignment Length:	298	Identity:	78/298 - (26%)
Similarity:	135/298 - (45%)	Gaps:	34/298 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 NAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEE----HLLEETE--EPYEICEQNEQPQVKVPA 144
            :.::.|:|.|..|.    .::.|::.|   |.||    :::||.:  |.::....:|:|.:....
Zfish    10 DVKIEETFTVKQED----LQKQTDLMV---LKEETLHQNVMEEKQQFEKHQDITTDEKPTLTKKT 67

  Fly   145 QEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQCGRHFTCPS 209
            ..:...|.:|      :...|  :.:..|..:|:..:.: |.::.....:...|||||:.|:...
Zfish    68 SSRGRPRKSK------SGCNF--SCKQCRKSFSQKPKLD-VHMRVHTGGKPYTCEQCGKSFSQKQ 123

  Fly   210 NFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQHERMR 274
            :||.|:..|||.:.:.|.||.::|........|:.:|.|...:.|:.|..::.|......|.|:
Zfish   124 SFKTHMRIHTGERPYTCQQCGKRFNHVGNFAAHKRIHTGERKYTCQQCGKSFYNTGNLAVHMRI- 187

  Fly   275 HTNVKPFTCKECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKGHAHTSS- 338
            ||..:|::|.:|.|||..:..|:.||.:|||.|.|.|..|..||.::..|..|.|    .||..
Zfish   188 HTGEEPYSCSQCGKSFKQNVTLKIHMRTHTGERRFTCTQCGKSFSQKQDLGIHMR----IHTGEK 248

  Fly   339 ----AQAALDNPVELDVKASNGMQTGAKDEALL--GKS 370
                .:.....|.:..:|......||.|..|.:  |||
Zfish   249 PYKCTECGKGFPYKSTLKHHMISHTGEKPFACVQCGKS 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871
		C2H2 Zn finger	198..218	CDD:275368	9/19 (47%)
		C2H2 Zn finger	226..243	CDD:275368	4/16 (25%)
		C2H2 Zn finger	254..275	CDD:275368	5/20 (25%)
		zf-C2H2	281..303	CDD:278523	8/21 (38%)
		C2H2 Zn finger	283..303	CDD:275368	8/19 (42%)
		zf-H2C2_2	296..320	CDD:290200	12/23 (52%)
		C2H2 Zn finger	311..329	CDD:275368	6/17 (35%)
znf1070	NP_001108190.1	C2H2 Zn finger	84..104	CDD:275368	3/20 (15%)
		COG5048	<88..329	CDD:227381	61/205 (30%)
		C2H2 Zn finger	112..132	CDD:275368	9/19 (47%)
		C2H2 Zn finger	140..160	CDD:275368	5/19 (26%)
		C2H2 Zn finger	168..188	CDD:275368	5/20 (25%)
		C2H2 Zn finger	196..216	CDD:275368	8/19 (42%)
		C2H2 Zn finger	224..244	CDD:275368	7/23 (30%)
		C2H2 Zn finger	252..272	CDD:275368	2/19 (11%)
		C2H2 Zn finger	280..300	CDD:275368	3/7 (43%)
		C2H2 Zn finger	308..328	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10725
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910