DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1792 and znf341

DIOPT Version :9

Sequence 1:	NP_651878.1	Gene:	CG1792 / 43727	FlyBaseID:	FBgn0039860	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	NP_001108045.1	Gene:	znf341 / 100136854	ZFINID:	ZDB-GENE-080204-99	Length:	796	Species:	Danio rerio

Alignment Length:	331	Identity:	78/331 - (23%)
Similarity:	121/331 - (36%)	Gaps:	77/331 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FCSTP-SNLFEEPNSVMLHQIEVLTGLFLLGGPGNELPPFICSPCELDLQTAIAFRERVIRTQKT 77
            |||.. |:.|:..:.:..|:             |.::...:...|....|....|.|.:...|:.
Zfish   420 FCSDKFSSYFQLKSHMTQHK-------------GEQVYRCVLKSCSQTFQKLDQFLEHIHTHQEQ 471

  Fly    78 LQESPNLGNAELIESFAVGVEKEIQYAEEVTEIEVIDLLPEEHLLEETEEPYEICEQNEQPQVKV 142
            |....:..:......|.:|:.   ||..        ...|::...:||.  |..|.:.:......
Zfish   472 LTYRCHQCSKVFPSLFELGLH---QYTH--------SFCPQQSQRKETS--YYRCMKCQSKYSTQ 523

  Fly   143 PAQEKKLRRSTKTTPTVFTSVKFADNSQATRTQWSRLTEDEVVALKRERRKRDCICEQCGRHFTC 207
            .|.|:.|..:|...|                                        |..|.:.|.|
Zfish   524 EALEQHLLNATHNYP----------------------------------------CPHCQKVFPC 548

  Fly   208 PSNFKLHLLRHTGVKSFACDQCSQQFYTATLLRRHQELHAGNALFQCRYCEATYSNASGRIQHER 272
            ...|:.||..|.....|.|..|.:.|.|...|:.|.::|:|...|:|..||||: |...:::...
Zfish   549 ERYFRRHLSTHGVGGKFKCQICKKFFKTEHYLKLHTQIHSGEKPFKCSVCEATF-NRKDKVKRHM 612

  Fly   273 MRHTNVKPFTCK-----ECNKSFAMSGKLRTHMLSHTGVRAFHCDSCQVSFVRRSHLTSHYRSKG 332
            :.|...|.:.|.     .|.|.|....||:.|:|||:|::.|.|..||.||.||:|:..|.||
Zfish   613 LIHEPFKKYKCPFRTHVGCTKEFNRPDKLKAHILSHSGIKPFKCQVCQKSFSRRAHMLEHQRS-- 675

  Fly   333 HAHTSS 338
              ||.:
Zfish   676 --HTDN 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1792	NP_651878.1	zf-AD	6..80	CDD:214871	13/66 (20%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		C2H2 Zn finger	226..243	CDD:275368	5/16 (31%)
		C2H2 Zn finger	254..275	CDD:275368	6/20 (30%)
		zf-C2H2	281..303	CDD:278523	8/26 (31%)
		C2H2 Zn finger	283..303	CDD:275368	8/24 (33%)
		zf-H2C2_2	296..320	CDD:290200	12/23 (52%)
		C2H2 Zn finger	311..329	CDD:275368	9/17 (53%)
znf341	NP_001108045.1	COG5048	295..676	CDD:227381	76/326 (23%)
		C2H2 Zn finger	296..316	CDD:275368
		zf-H2C2_2	308..333	CDD:290200
		C2H2 Zn finger	324..344	CDD:275368
		C2H2 Zn finger	418..438	CDD:275368	5/17 (29%)
		C2H2 Zn finger	446..468	CDD:275368	4/21 (19%)
		C2H2 Zn finger	476..496	CDD:275368	4/22 (18%)
		C2H2 Zn finger	513..535	CDD:275370	4/21 (19%)
		C2H2 Zn finger	539..559	CDD:275368	7/19 (37%)
		C2H2 Zn finger	567..587	CDD:275368	6/19 (32%)
		zf-H2C2_2	579..604	CDD:290200	10/25 (40%)
		C2H2 Zn finger	595..615	CDD:275368	6/20 (30%)
		C2H2 Zn finger	623..648	CDD:275368	8/24 (33%)
		zf-H2C2_2	641..665	CDD:290200	12/23 (52%)
		C2H2 Zn finger	656..676	CDD:275368	11/23 (48%)
		C2H2 Zn finger	684..701	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930