Sequence 1: | NP_524610.1 | Gene: | Med / 43725 | FlyBaseID: | FBgn0011655 | Length: | 771 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_110485.1 | Gene: | Smad7 / 81516 | RGDID: | 69314 | Length: | 426 | Species: | Rattus norvegicus |
Alignment Length: | 454 | Identity: | 106/454 - (23%) |
---|---|---|---|
Similarity: | 152/454 - (33%) | Gaps: | 157/454 - (34%) |
- Green bases have known domain annotations that are detailed below.
Fly 389 GGAAAGGQYYGQPPPVSQMQGAGGGGTS-----VAPSVHAQQNGYVSQPGSAGSAPVGG------ 442
Fly 443 -------------------------GGV--------------FGTAQPTPQQPQQPPTGVQ---- 464
Fly 465 ----------------------ANTGSAGAQAGAGGGAAGTWTGPNTLTYTQSMQ-PPDPRS-LP 505
Fly 506 GGFWNSSL--------SGDLGSPQQTPPQQQQQQQQPRLLSRQPPPEYWCSIAYFELDTQVGETF 562
Fly 563 KV--PSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRCL 625
Fly 626 SDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQC--------HQQMHSLATNAQAAAA 682
Fly 683 AQAAAVAGVANQQMGGGGRSMTAAAGIGVDDLRRLCILRLSFVKGWGPDYPRQSIKETPCWIEV 746 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Med | NP_524610.1 | MH1_SMAD_4 | 42..166 | CDD:199816 | |
MH2_SMAD_4 | 543..760 | CDD:199823 | 65/214 (30%) | ||
Smad7 | NP_110485.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 14..40 | 4/10 (40%) | |
MH1_SMAD_7 | 60..205 | CDD:199818 | 18/152 (12%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 67..88 | 4/20 (20%) | |||
Important for interaction with SMURF2. /evidence=ECO:0000250 | 208..217 | 4/8 (50%) | |||
PY-motif. /evidence=ECO:0000250 | 208..211 | 1/2 (50%) | |||
MH2_SMAD_7 | 254..424 | CDD:199825 | 65/218 (30%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3701 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |