Protein Alignment Med and daf-14

DIOPT Version :9

• Sequence 1: NP_524610.1
• Gene: Med / 43725
• FlyBaseID: FBgn0011655
• Length: 771
• Species: Drosophila melanogaster
• Sequence 2: NP_001255475.1
• Gene: daf-14 / 177908
• WormBaseID: WBGene00000910
• Length: 331
• Species: Caenorhabditis elegans
• Alignment Length: 322
• Identity: 76/322 - (23%)
• Similarity: 127/322 - (39%)
• Gaps: 87/322 - (27%)

  Fly   480 AAGTWTGPNTLTYTQSMQPP------------------------DPRSLPGGFWNSSLSGDL--G 518
            |||.:..|:.:....|:..|                        |..:.|..|.|.|....|  .
 Worm    40 AAGNYMYPDQVHLPASINNPNMPINDWLEDAPMPDCYNVPSTSTDENNDPFPFSNISSQSSLKPK 104

  Fly   519 SPQQT-----PPQQQQQQQQPRLLSRQPPPEYWCSIAYFELDTQVGETFKVPSAK-PNVIIDGYV 577
            :|::.     |...:....:|:....:.|   ||:|.|:||..::|:.|:   || |.:.|||
 Worm   105 TPEKAVVEVRPTGNEMLDPEPKYPKEEKP---WCTIFYYELTVRLGKAFE---AKVPTITIDG-- 161

  Fly   578 DPSGGNRFCLGALSN--VHRTEQSERARLHIGKGVQLDLRGEGDVWLRCLSDNSVFVQSYYLDRE 640
             .:|.:..|..:|::  ..|..:|.:.|..:|.|:||... .|::||..|:|..||||..:|::.
 Worm   162 -ATGASDECRMSLTSQPSSRNSKSSQIRNTVGAGIQLAYE-NGELWLTVLTDQIVFVQCPFLNQT 224

  Fly   641 AGR---------TPGDAVHKIYPAACIKVFDLRQCHQQMHSLATNAQAAAAAQAAAVAGVANQQM 696
            ..:         ..||...       :|:||..|..|:              :..|:..:..::
 Worm   225 LNKPLKYVFRLQNKGDQKR-------MKIFDKEQFEQE--------------KTLALGPLTEKE- 267

  Fly   697 GGGGRSMTAAAGIGVDDLRRLCILRLSFVKGWGPDYPRQSIKETPCWIEVHLHRALQLLDEV 758
                        :..:.:|....:|:||.||:|..|.|..:...|||||:.||......|.|
 Worm   268 ------------VADERMRIFSNIRVSFCKGFGETYSRLKVVNLPCWIEIILHEPADEYDTV 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Med	NP_524610.1	MH1_SMAD_4	42..166	CDD:199816
		MH2_SMAD_4	543..760	CDD:199823	60/228 (26%)
daf-14	NP_001255475.1	DWB	133..308	CDD:197770	57/218 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910