Sequence 1: | NP_524610.1 | Gene: | Med / 43725 | FlyBaseID: | FBgn0011655 | Length: | 771 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001036125.1 | Gene: | Smad7 / 17131 | MGIID: | 1100518 | Length: | 426 | Species: | Mus musculus |
Alignment Length: | 455 | Identity: | 105/455 - (23%) |
---|---|---|---|
Similarity: | 153/455 - (33%) | Gaps: | 159/455 - (34%) |
- Green bases have known domain annotations that are detailed below.
Fly 389 GGAAAGGQYYGQPPPVSQMQGAGGGGTS-----VAPSVHAQQNGYVSQPGSAGSAPVGG------ 442
Fly 443 -------------------------GGV--------------FGTAQPTPQQPQQPPTGVQ---- 464
Fly 465 ----------------------ANTGSAGAQAGAGGGAAGTWTGPNTLTYTQSMQ-PPDPRS-LP 505
Fly 506 GGFWNSSLSGDLGSPQQTPPQQQQ---------QQQQPRLLSRQPPPEYWCSIAYFELDTQVGET 561
Fly 562 FKV--PSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRC 624
Fly 625 LSDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQC--------HQQMHSLATNAQAAA 681
Fly 682 AAQAAAVAGVANQQMGGGGRSMTAAAGIGVDDLRRLCILRLSFVKGWGPDYPRQSIKETPCWIEV 746
Fly 747 746 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Med | NP_524610.1 | MH1_SMAD_4 | 42..166 | CDD:199816 | |
MH2_SMAD_4 | 543..760 | CDD:199823 | 65/214 (30%) | ||
Smad7 | NP_001036125.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 14..42 | 5/12 (42%) | |
MH1_SMAD_7 | 60..205 | CDD:199818 | 17/152 (11%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 67..87 | 2/19 (11%) | |||
Important for interaction with SMURF2. /evidence=ECO:0000250 | 208..217 | 4/8 (50%) | |||
PY-motif. /evidence=ECO:0000250 | 208..211 | 1/2 (50%) | |||
MH2_SMAD_7 | 254..424 | CDD:199825 | 65/218 (30%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3701 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |