Protein Alignment CycG and CCNB3

DIOPT Version :9

• Sequence 1: NP_001263146.1
• Gene: CycG / 43724
• FlyBaseID: FBgn0039858
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_016885402.1
• Gene: CCNB3 / 85417
• HGNCID: 18709
• Length: 1404
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 97/591 - (16%)
• Similarity: 192/591 - (32%)
• Gaps: 172/591 - (29%)

  Fly    13 EYAAEVDCELESTLQQQQQLHLQQQYEQYQHYQYQREQDIAYYCQLQAARQQEQLMQQRTSMSSS 77
            |.:.:.:...:.||..|::..::|:....:|                :|..::...::.|....|
Human   847 EPSVDTEAHFKETLALQEKPSIEQEALFKRH----------------SALWEKPSTEKETIFKES 895

  Fly    78 VMPGLALPQDHQDHPA----ALLNGPHNNNIGLAMDAHSIN-AILVDD-----EQPST------- 125
            :        |.|:.|:    .||..|      ||:...:|| |:|.:|     |:|:|
Human   896 L--------DLQEKPSIKKETLLKKP------LALKMSTINEAVLFEDMIALNEKPTTGKELSFK 946

  Fly   126 -----------------------------SAQAAAAAAASAGGSAGAGSGSGLGGAIGGGKLANG 161
                                         :..:.|..:.::..|....:..|..|.|....|...
Human   947 EPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVGKSGTINEAFLFED 1011

  Fly   162 INRNAEMPTDWMRIADE----------------------GRYGT-PGAAGLEYQKYEQQQQLEDL 203
            :....|.||....::.:                      .:.|| |.......:...::..:..:
Human  1012 MITLNEKPTTGKELSFKEPLALQESPTCKEDTFLETFLIPQIGTSPYVFSTTPESITEKSSIATM 1076

  Fly   204 AE-------SEAGAVGGASNN------NGESSSSLKKLED--------QLHALTSDELYETLKEY 247
            ..       :|:.|...||:.      .|.....:...||        ..:.:.:.|::..:||.
Human  1077 TSVGKSRTTTESSACESASDKPVSPQAKGTPKEQITPREDIDEDSSDPSFNPMYAKEIFSYMKER 1141

  Fly   248 DVLQD-KFHTVLLLPKESRR--EVTAGGRDGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMA 309
            ::.:. :.|...:|.....|  |:|:..|......|..:::.:|:..:.|:.|:.|||.:|.:..
Human  1142 EIEETAQSHEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAV 1206

  Fly   310 VKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPIT 374
            .|...:..:...:|.:|.|..:......:|.|.|........::..|...|.|.|...: :.||.
Human  1207 CKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDI-NIPIA 1270

  Fly   375 SVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELENRLEILMCDV----------KTTVITPS 429
                   |:             |.:.|.:.|........|...:|::          |.:.:..:
Human  1271 -------YH-------------FLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAA 1315

  Fly   430 TLALVLICLHLDFHIKESYTRGSPELKHVFEY-ILFLQQYMRIPDRVFTCGFSIVSGILSHYNGQ 493
            :|.|.|....|.:.:        |.|:|...| |..|...:|..:::.|         .|.|:..
Human  1316 SLLLALYMKKLGYWV--------PFLEHYSGYSISELHPLVRQLNKLLT---------FSSYDSL 1363

  Fly   494 NKAPYK 499
            ....||
Human  1364 KAVYYK 1369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	17/77 (22%)
CCNB3	XP_016885402.1	Cyclin_N	1133..1266	CDD:306612	28/133 (21%)
		Cyclin_C	1268..1384	CDD:308564	25/139 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900