Protein Alignment CycG and CLN3

DIOPT Version :9

• Sequence 1: NP_001263146.1
• Gene: CycG / 43724
• FlyBaseID: FBgn0039858
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_009360.1
• Gene: CLN3 / 851191
• SGDID: S000000038
• Length: 580
• Species: Saccharomyces cerevisiae
• Alignment Length: 504
• Identity: 93/504 - (18%)
• Similarity: 153/504 - (30%)
• Gaps: 184/504 - (36%)

  Fly   210 AVGGASNNNGESSSSLKKLEDQLHALTSDELYETLKEY--DVLQDKF---HT----VLLLPKESR 265
            |:..|.:.|    .:|.|.|.|.|       :..:.||  |.|...|   ||    ..|....|:
Yeast    47 AIASAKSKN----PNLVKRELQAH-------HSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQ 100

  Fly   266 REVTAGGR----DGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASF--- 323
            .:|....|    |   :::.| .....|.:..||...:::|::..|..:|..:...:|:.:.
Yeast   101 PQVNPKMRFLIFD---FIMYC-HTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWIS 161

  Fly   324 -----------------HLAIKQLDLKPIPAEDL-----VTISQCGCTAGD-------------- 352
                             :|...|..:|.....::     :..|.|.....|
Yeast   162 SKFWDSKNRMATLKVLQNLCCNQYSIKQFTTMEMHLFKSLDWSICQSATFDSYIDIFLFQSTSPL 226

  Fly   353 --------------------LERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAK---EIG 394
                                |...||...||.....|  |..:::.:::...:...||.   |:.
Yeast   227 SPGVVLSAPLEAFIQQKLALLNNAAGTAINKSSSSQG--PSLNINEIKLGAIMLCELASFNLELS 289

  Fly   395 GDFFKFYQQLI-------------------------KLEELENRLEILMCDVKTTVIT------- 427
               ||:.:.||                         .|||....|:|.:.::..|::.
Yeast   290 ---FKYDRSLIALGAINLIKLSLNYYNSNLWENINLALEENCQDLDIKLSEISNTLLDIAMDQNS 351

  Fly   428 -PSTL------------------ALVLICLHLDFHIKESYTRGSPELKHVFEYILFLQQYMRIPD 473
             ||:.                  ||...|:.|  .::|.|.  |.||:.::..| |.|.:   ..
Yeast   352 FPSSFKSKYLNSNKTSLAKSLLDALQNYCIQL--KLEEFYR--SQELETMYNTI-FAQSF---DS 408

  Fly   474 RVFTCGFS--------IVSGILSHYNGQNKAPYKQRLVWKLSSRTLRVLRPINRFSSDLP----- 525
            ...||.:|        .||...:.|...:  .:.:||. |.|........|.:..||..|
Yeast   409 DSLTCVYSNATTPKSATVSSAATDYFSDH--THLRRLT-KDSISPPFAFTPTSSSSSPSPFNSPY 470

  Fly   526 ------TIEEGIPNALDDGLRSRTE-------SISSEEEEDWPTSPIIP 561
                  |..:...:....|..|.|:       ||.......|| ||:.|
Yeast   471 KTSSSMTTPDSASHHSHSGSFSSTQNSFKRSLSIPQNSSIFWP-SPLTP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	18/136 (13%)
CLN3	NP_009360.1	COG5024	35..576	CDD:227357	93/504 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900