DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycG and CYCA1;1

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_175077.1	Gene:	CYCA1;1 / 841014	AraportID:	AT1G44110	Length:	460	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	91/507 - (17%)
Similarity:	169/507 - (33%)	Gaps:	137/507 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 LMQQRTSMSSSVMPGLALPQ--DHQDHPAALL------NGPHNNNIGLAMDAHSINAILVDDEQP 123
            |..:|:|.|||....||..|  ...::...|:      ..|.:|.....:.:...|:..|.....
plant     5 LQNRRSSFSSSTKSSLAKRQAPSSSENSVKLMPAMTKKRAPLSNITNQKIASRLQNSDSVHCSNK 69

  Fly   124 STSAQAAAAAAASAGGSAGAGSGSGLGGAIGGGKLANGINR--NAEMPTDWMRIADEGRYGTPGA 186
            |...:.|.:...:|..|      |.|..:|...|:|:..::  :..:..|..|.:.:. |.:|..
plant    70 SAKLKIAPSVCVNASFS------SNLQQSIVPHKVASSPSKSDDGSVSMDETRSSSDS-YKSPQV 127

  Fly   187 AGLE--------------------------YQKYEQQQQLEDLAESEAGAVGGASNNNGESSSSL 225
            ..:|                          ...|..:..|.|:.:.:...:....:|||
plant   128 EYIENDDVSAVVSIERKALSNLFITPNSETIDNYCSRDVLSDMKKMDKNQIVNIDSNNG------ 186

  Fly   226 KKLEDQLHALTSDELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGR---DGSAYVLRCLKMW- 286
               :.||.|..:.::|:.|:..:.             :.|.:|....|   |.::.:...|..|
plant   187 ---DPQLCATFACDIYKHLRASEA-------------KKRPDVDYMERVQKDVNSSMRGILVDWL 235

  Fly   287 ------YELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQ 345
                  |.|..:.|:..::.:||:|....:..:.:..:.||...:|.|..::.....|:...|:.
plant   236 IEVSEEYRLVPETLYLTVNYIDRYLSGNVISRQKLQLLGVACMMIAAKYEEICAPQVEEFCYITD 300

  Fly   346 CGCTAGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEEL 410
            ......::..|...:.|.|..:| .|| |:..:||.:......:.:          ..|::||.:
plant   301 NTYLKDEVLDMESDVLNYLKFEM-TAP-TTKCFLRRFVRAAHGVHE----------APLMQLECM 353

  Fly   411 ENRL-EILMCDVKTTVITPSTLALVLICLHLDFHIKESYTRGSPELKHVFEYILFLQQYMRIPDR 474
            .|.: |:.:.:......:||.:|...|                           ||.:|:..|.|
plant   354 ANYIAELSLLEYTMLSHSPSLVAASAI---------------------------FLAKYILDPTR 391

  Fly   475 VFTCGFSIVSGILSHYNGQNKAPYK-----------QRLVWKLSSRTLRVLR 515
                  ...:..|.||     ..||           |||.......||..:|
plant   392 ------RPWNSTLQHY-----TQYKAMELRGCVKDLQRLCSTAHGSTLPAVR 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	14/77 (18%)
CYCA1;1	NP_175077.1	CYCLIN_AtCycA_like_rpt1	187..322	CDD:410265	26/147 (18%)
CYCA1;1	NP_175077.1	CYCLIN_AtCycA-like_rpt2	326..440	CDD:410210	29/156 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810