DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and CYCB1;3

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_187759.2	Gene:	CYCB1;3 / 820325	AraportID:	AT3G11520	Length:	414	Species:	Arabidopsis thaliana

Alignment Length:	485	Identity:	92/485 - (18%)
Similarity:	168/485 - (34%)	Gaps:	123/485 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 PQDHQDHPAALLNGPHNNNIGLAMDAHSINAILVDD----EQPST---------SAQAAAAAAAS 136
            ||..:..|..|.|....|...|. |..::::::..:    .:|.|         :||.||||...
plant     9 PQPVRGDPIDLKNAAAKNRRALG-DIGNVDSLIGVEGGKLNRPITRNFRAQLLENAQVAAAANKK 72

  Fly   137 AGGSAGAGSGSGLGGAIGGGKLANGINRNAEMPTDWMRIADEGRYGTPGAAGLEYQKYEQQQQLE 201
            |                   .:.:|:.:..|:    :|...:...|         .|.|..:.:|
plant    73 A-------------------PILDGVTKKQEV----VRAVQKKARG---------DKREPSKPIE 105

  Fly   202 DLAES-EAGAVGGASNNNGE-SSSSLKKLEDQLHALTSDELYETLKEYDV-----LQDKFHTVLL 259
            .:..| :...|..|..|..: :.||:.....:..:.|.|..|.. ||.|:     ::|.:.....
plant   106 VIVISPDTNEVAKAKENKKKVTYSSVLDARSKAASKTLDIDYVD-KENDLAAVEYVEDMYIFYKE 169

  Fly   260 LPKESRREVTAGGRDGSAYVLRCLKM-W-------YELPSDVLFSAMSLVDRFLDRMAVKPKHMA 316
            :..||:.::....:......:|.:.: |       ::|..:.|:..::::||||....|..:.:.
plant   170 VVNESKPQMYMHTQPEIDEKMRSILIDWLVEVHVKFDLSPETLYLTVNIIDRFLSLKTVPRRELQ 234

  Fly   317 CMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPITSVSYLRI 381
            .:.|::..:|.|..::.|....|||.::.....:..:..|...|...|           ..||.:
plant   235 LVGVSALLIASKYEEIWPPQVNDLVYVTDNSYNSRQILVMEKTILGNL-----------EWYLTV 288

  Fly   382 --YYALFRNLAKEIGGDFFKFYQQLIKLEELENRL-EILMCDVKTTVITPSTLALVLI-----CL 438
              .|.......|..|.|        .|||.|.:.| |:.:....:.:..||.||...:     ||
plant   289 PTQYVFLVRFIKASGSD--------QKLENLVHFLAELGLMHHDSLMFCPSMLAASAVYTARCCL 345

  Fly   439 H--------LDFHIKESYTRGSPELKHVFEYILFLQQYMRIPDRVFTCGFSIVSGILSHYNGQNK 495
            :        |.||...|    ..:|....:.:.|:..         ..|.|.:.|:|..|:
plant   346 NKTPTWTDTLKFHTGYS----ESQLMDCSKLLAFIHS---------KAGESKLRGVLKKYS---- 393

  Fly   496 APYKQRLVWKLSSRTLRVLRPINRFSSDLP 525
                     ||....:.::.|.....|..|
plant   394 ---------KLGRGAVALISPAKSLMSSAP 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	16/77 (21%)
CYCB1;3	NP_187759.2	Cyclin_N	162..287	CDD:278560	23/135 (17%)
CYCB1;3	NP_187759.2	Cyclin_C	289..406	CDD:281044	29/150 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810