Protein Alignment CycG and CCNI2

DIOPT Version :10

• Sequence 1: NP_524609.2
• Gene: CycG / 43724
• FlyBaseID: FBgn0039858
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001274181.1
• Gene: CCNI2 / 645121
• HGNCID: 33869
• Length: 385
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 89/365 - (24%)
• Similarity: 135/365 - (36%)
• Gaps: 86/365 - (23%)

  Fly   122 QPSTSAQAAAAAAASAGGSAGAG-----SGSGLGGAIGGGKLANGINRNAEMPTDWMRIADEGRY 181
            |||:|   ..:|..|.||..|||     .|..|..:.|...|... || :..|
Human    10 QPSSS---EVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRS-NR-SRCP------------ 57

  Fly   182 GT--PGAAGLEYQKYE---QQQQLEDLAESEAGAVGGASNNN----GESSSSLKKLEDQLH---- 233
            ||  ||||.|......   :.::....|...|.||..|:...    ...|...:.||..|.
Human    58 GTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDERRL 122

  Fly   234 ----ALTSD---ELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKMWYELPS 291
                .|..|   .|:...|..|.:.|.|..|:|                  ::||....:|.  |
Human   123 LCHLQLAQDREARLWRGGKPQDEICDAFEEVVL------------------WLLRLQNTFYF--S 167

  Fly   292 DVLFS-AMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKP-IP-AEDLVTISQCGCTAGDL 353
            ...|: |:::..|.|..:.||.|::.|.::.|..||.|..:.:. || .:|.........:..:|
Human   168 QSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNEL 232

  Fly   354 ERMAGVIANKL--GVQMGHAPITSVSYLRI-YYALFRNLAKEIGGDFFKF----YQQLIKL---- 407
            .||...|.::|  .:.:|    |.:.:|.| .|.:|.:..|..|..|...    :..:::|
Human   233 LRMELAILDRLHWDLYIG----TPLDFLTIEKYGVFCSNIKNHGLQFHALVVLSWPHVLELLPQR 293

  Fly   408 ------EELENRLEILMCDVKTTVITPSTLALVLICLHLD 441
                  ..|..:|:..|...:......||||||:|.|.|:
Human   294 NPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELE 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_524609.2	CYCLIN_CCNG	273..364	CDD:410227	23/93 (25%)
CCNI2	NP_001274181.1	PRK12323	<3..>111	CDD:481241	31/117 (26%)
		CYCLIN_SF	151..247	CDD:477360	26/115 (23%)