DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and Ccnd2

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_071603.2	Gene:	Ccnd2 / 64033	RGDID:	621083	Length:	288	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	48/217 - (22%)
Similarity:	77/217 - (35%)	Gaps:	45/217 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 DELYETLKEYDVLQDKFHTVLL------LPKESRREVTAGGRDGSAYVLRCLKMW-------YEL 289
            |.:...:.:.::|:|:....||      ||:.|..:...  :|...|:.|.:..|       .:.
  Rat     9 DPVRRAVPDRNLLEDRVLQNLLTIEERYLPQCSYFKCVQ--KDIQPYMRRMVATWMLEVCEEQKC 71

  Fly   290 PSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLE 354
            ..:|...||:.:||||..:.....|:..:......||.|..:..|:.||.|...:.......:|.
  Rat    72 EEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSVKPQELL 136

  Fly   355 RMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFF-----KFYQQLIKLEELENRL 414
            ....|:..||.                     .|||.....||.     |..||..||..:....
  Rat   137 EWELVVLGKLK---------------------WNLAAVTPHDFIEHILRKLPQQKEKLSLIRKHA 180

  Fly   415 E--ILMC--DVKTTVITPSTLA 432
            :  |.:|  |.|..:..||.:|
  Rat   181 QTFIALCATDFKFAMYPPSMIA 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	18/77 (23%)
Ccnd2	NP_071603.2	CYCLIN_SF	1..149	CDD:424085	31/162 (19%)
		CYCLIN_CCND2_rpt2	154..258	CDD:410280	14/49 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..288
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910