DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and ccne2

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001016267.1	Gene:	ccne2 / 549021	XenbaseID:	XB-GENE-923043	Length:	397	Species:	Xenopus tropicalis

Alignment Length:	236	Identity:	45/236 - (19%)
Similarity:	90/236 - (38%)	Gaps:	36/236 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   287 YELPSDVLFSAMSLVDRF-LDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTA 350
            |.|..:..:.|....||| |.:..|....:..:.|.:..:|.|..::.|....:...::...|:.
Frog   155 YTLHRETFYLAQDFFDRFMLTQTCVNKSMLQLIGVTALFIASKLEEIYPPKLHEFAYVTDGACSE 219

  Fly   351 GDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALF------RNLAKEIGGDFFKFYQQLIKL-- 407
            .|:.:|..::...|..::  .|:|::::|.:|..:.      :.|..:...:.|....||:.|
Frog   220 DDILQMELIMLKALKWEL--YPVTAIAWLNLYLQVSSLKDHPKLLLPQYSQEQFIHVVQLLDLCI 282

  Fly   408 ---EELENRLEILMCD-----VKTTVITPST---LALVLICLHLDFHIKESYTRGSPELKHVFEY 461
               ..|:.:..||...     ..|.|:|.:|   :..:..|:|..........|.||....||:.
Frog   283 LHHTSLDFQYRILAAAALYHFTSTEVVTKATGLDMESIGECVHWMAPFARVVKRSSPFKLKVFKK 347

  Fly   462 I--------------LFLQQYMRIPDRVFTCGFSIVSGILS 488
            :              |.:...:::||.........:.|||:
Frog   348 VAPEDMHNIQTHANYLDMLDDVKVPDSDLGESPVAIGGILT 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	15/78 (19%)
ccne2	NP_001016267.1	Cyclin_N	111..237	CDD:365896	16/81 (20%)
ccne2	NP_001016267.1	Cyclin_C	240..359	CDD:367282	22/118 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910