DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and ccni

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_012814707.1	Gene:	ccni / 448195	XenbaseID:	XB-GENE-945654	Length:	383	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	55/220 - (25%)
Similarity:	102/220 - (46%)	Gaps:	44/220 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   257 VLLLP-KESRRE----------VTAGG----------------RDGSAYVLRCLKMWYELPSDVL 294
            :|||| :.:|.|          |..||                ||.....|..||..:.:..:..
Frog     5 LLLLPGRVARTEDKDWNIHLWRVWMGGPDLASLFLDVGISPEQRDEVILWLAELKYQFRVYPETH 69

  Fly   295 FSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDL-KPIPAEDLVTI-SQCGCTAGDLERMA 357
            ..|:|::||||..:..:||::.|::::.|.||.|.::. :.||...::|. |.|||:..::.||.
Frog    70 ALAISILDRFLAAVKARPKYLRCIAISCFFLAAKTIEEDERIPVLRVLTQGSSCGCSPAEVLRME 134

  Fly   358 GVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELEN----RLEILM 418
            .:|.:||...:..|  |.:.:|.|::|:..|.:.|:       :.::.:|...::    ..::|.
Frog   135 RIILDKLNWDLHTA--TPLDFLHIFHAMTLNASPEL-------FDRIPELNPSQHVALLTRQLLQ 190

  Fly   419 CDV--KTTVITPSTLALVLICLHLD 441
            |..  :......|.|||.|:.|.::
Frog   191 CMAFHQLLQFKGSMLALALLSLEME 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	24/79 (30%)
ccni	XP_012814707.1	CYCLIN_CCNI-like	47..145	CDD:410230	30/97 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I9962
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910