DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and cig2

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_593889.1	Gene:	cig2 / 2543481	PomBaseID:	SPAPB2B4.03	Length:	411	Species:	Schizosaccharomyces pombe

Alignment Length:	216	Identity:	43/216 - (19%)
Similarity:	90/216 - (41%)	Gaps:	38/216 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 SNNNGESSSSLKK-----LEDQL--HALTSD----ELYETLKEYDVLQDKFHTVLLLPK--ESRR 266
            |.|...|..:|:|     ::|.|  :.|.::    |::|.:::.|:      ..|..||  :.::
pombe   104 SKNADPSVETLQKDRVSNVDDHLSSNPLMAEEYAPEIFEYIRKLDL------KCLPNPKYMDQQK 162

  Fly   267 EVTAGGRDGSAYVLRCLKMW-------YELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFH 324
            |:|...|:       .|..|       :.|..:.|:.|::::||||.|.:..........:.:..
pombe   163 ELTWKMRE-------ILNEWLVEIHSNFCLMPETLYLAVNIIDRFLSRRSCSLSKFQLTGITALL 220

  Fly   325 LAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGH-APIT---SVSYLRIYYAL 385
            :|.|..::.....::.|.::....|..|:......:.|.|...:.: :|:.   .:|....|.|.
pombe   221 IASKYEEVMCPSIQNFVYMTDGAFTVEDVCVAERYMLNVLNFDLSYPSPLNFLRKISQAEGYDAQ 285

  Fly   386 FRNLAKEIGGDFFKFYQQLIK 406
            .|.|.|.: .:.:.|...|::
pombe   286 TRTLGKYL-TEIYLFDHDLLR 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	14/77 (18%)
cig2	NP_593889.1	COG5024	1..399	CDD:227357	43/216 (20%)
		Cyclin_N	139..265	CDD:278560	26/138 (19%)
		Cyclin_C	267..382	CDD:281044	9/40 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810