DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and Ccng1

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_037055.1	Gene:	Ccng1 / 25405	RGDID:	2295	Length:	294	Species:	Rattus norvegicus

Alignment Length:	315	Identity:	93/315 - (29%)
Similarity:	152/315 - (48%)	Gaps:	42/315 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 LHALTSD------ELYETLKEYDVLQDKFHTVLLLPKESRRE----VTAGGRDGSAYVLRCLKMW 286
            :..||:|      :|...|::....|.|...:.|:  ||..:    :||..||.....|..|..:
  Rat     2 IEVLTTDSQKLLHQLNTLLEQESRCQPKVCGLKLI--ESAHDNGLRMTARLRDFEVKDLLSLTQF 64

  Fly   287 YELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQL-DLKPIP-AEDLVTISQCGCT 349
            :...::....|::|:||||.:|.|:.||:.|:.::.|:||:|.: :.:.:| |.||:.|||...|
  Rat    65 FGFDTETFSLAVNLLDRFLSKMKVQAKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFT 129

  Fly   350 AGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFR-NLAKEIGGDFFKFYQQLIKLEELENR 413
            ..||.||..::..|:..::  ...|:..:|::||:|.| .|..|...|        :..|.||.:
  Rat   130 VSDLMRMEKIVLEKVCWKV--KATTAFQFLQLYYSLIRETLPFERRND--------LNFERLEAQ 184

  Fly   414 LEILMCDVKTTVITPSTLALVLICLHLDFHIKESYTRGSPELKHV--FEYILFLQQYMRIPDRVF 476
            |:...|.:..:...||.|||.:|.|.:.            .||:|  .|.:..:|::.:|..|..
  Rat   185 LKACHCRIIFSKAKPSVLALAIIALEIQ------------ALKYVELTEGVECIQKHSKISGRDL 237

  Fly   477 TCGFSIVSGILSHYNGQNKA--PYKQRLVWKLSSRTLRVLRPINRFSSDLPTIEE 529
            |....:||..|:.|: .||.  |..|:|.|.:|.||.|.|:......:.||||.|
  Rat   238 TFWQELVSKCLTEYS-SNKCSKPNGQKLKWIVSGRTARQLKHSYYRITHLPTIPE 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	28/79 (35%)
Ccng1	NP_037055.1	CYCLIN_CCNG1	50..147	CDD:410286	32/96 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9562
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2995
Inparanoid	1	1.050	110	1.000	Inparanoid score	I4793
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003985
OrthoInspector	1	1.000	-	-		otm44938
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2747
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.920