DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycG and Ccnf

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_006523617.1	Gene:	Ccnf / 12449	MGIID:	102551	Length:	790	Species:	Mus musculus

Alignment Length:	384	Identity:	74/384 - (19%)
Similarity:	132/384 - (34%)	Gaps:	132/384 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 QDHQDHPAALLNGPHNNNIGLAMDAHSINAI--LVDDEQPSTSAQAAAAAAASAGGSAGAGSGSG 148
            |..:.|.|::|              |.:..:  |.:||:....|::..             ..|.
Mouse   190 QLQRSHKASIL--------------HCLGRVLNLFEDEEKRKQARSLL-------------EESS 227

  Fly   149 LGGAIGGGKLANGINRNAEMPTDWMRIADEGR----------YGTPGAAGLEYQKYEQQQQLEDL 203
            ..|.:....|....:|..:|       :|.||          |...|.       :|.|     |
Mouse   228 RQGCLISSYLLWESDRKVDM-------SDPGRCLHSFRKLRDYAAKGC-------WEAQ-----L 273

  Fly   204 AESEAGAVGGASNNNGES-SSSLKKLEDQLHALTSDELYETLKEYDVLQDKFHTVL---LLPKES 264
            |.::|.|.|......|:: |.|:.:|.....|:...:::...|.   |.|....:|   |:...:
Mouse   274 ALAKACAGGSQLGLEGKACSESVCQLFQASQAVNKQQIFSVQKG---LSDTMRYILIDWLVEVAT 335

  Fly   265 RREVTAGGRDGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMAVKPKH------MACMSVASF 323
            .::.|:          .||.:..|           .|||:|.|..| |::      :|||.:.:.
Mouse   336 MKDFTS----------LCLHLTVE-----------CVDRYLRRRLV-PRYKLQLLGIACMVICTR 378

  Fly   324 HLAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPI-TSVSYLRIYYALFR 387
            .::.:.|.::     :.|.::.......||.|:.|.|.:.|   .|...| |.|.|
Mouse   379 FISKEILTIR-----EAVWLTDNTYKYEDLVRVMGEIISAL---EGKIRIPTVVDY--------- 426

  Fly   388 NLAKEIGGDFFKFYQQLIKLEELENRLEIL---MCDV-----KTTVITPSTLALVLICL 438
               ||:          |:.|..:..|.:.|   :|::     ..::..|:.||...:.|
Mouse   427 ---KEV----------LLTLVPVAPRTQHLCSFLCELTLLHTSLSIYAPARLASAALLL 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	18/83 (22%)
Ccnf	XP_006523617.1	FBOX	48..86	CDD:197608
		Cyclin_N	296..419	CDD:365896	30/155 (19%)
		Cyclin_C	438..544	CDD:367282	7/35 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900