DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycG and Ccne2

DIOPT Version :9

Sequence 1:	NP_001263146.1	Gene:	CycG / 43724	FlyBaseID:	FBgn0039858	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001032211.1	Gene:	Ccne2 / 12448	MGIID:	1329034	Length:	404	Species:	Mus musculus

Alignment Length:	214	Identity:	40/214 - (18%)
Similarity:	85/214 - (39%)	Gaps:	34/214 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 SDELYETL--KEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKM-W-------YELPS 291
            |.|:::.:  ||...:.||...||....|.:              :|.:.: |       |.|..
Mouse   110 SQEVWQNMLQKENRYVHDKHFQVLHSDLEPQ--------------MRSILLDWLLEVCEVYTLHR 160

  Fly   292 DVLFSAMSLVDRF-LDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLER 355
            :..:.|....||| |.:..|....:..:.:.|..:|.|..::.....::...::...|:..|:.:
Mouse   161 ETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEVDILK 225

  Fly   356 MAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQ--LIKLEELENRLEILM 418
            |...|...|..::  .|:|.:|:|.::..:  :..|::.......|.|  .|::.:|   |::.:
Mouse   226 MELNILKALKWEL--CPVTVISWLNLFLQV--DAVKDVPKVLLPQYSQETFIQIAQL---LDLCI 283

  Fly   419 CDVKTTVITPSTLALVLIC 437
            ..:.:.......||...:|
Mouse   284 LAIDSLEFQYRILAAAALC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycG	NP_001263146.1	CYCLIN	<287..365	CDD:294043	15/78 (19%)
Ccne2	NP_001032211.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41
		Cyclin_N	112..239	CDD:365896	26/142 (18%)
		Cyclin_C	241..361	CDD:367282	12/67 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810