DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL6 and rpl6

DIOPT Version :9

Sequence 1:	NP_651876.1	Gene:	RpL6 / 43723	FlyBaseID:	FBgn0039857	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001003844.2	Gene:	rpl6 / 336727	ZFINID:	ZDB-GENE-030131-8671	Length:	265	Species:	Danio rerio

Alignment Length:	278	Identity:	128/278 - (46%)
Similarity:	176/278 - (63%)	Gaps:	29/278 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAPIEKAKKVAKSAKKGKKHPVNSYLKGGILRYSKAQMYKRRALY-------------RLKDKKS 52
            ||..:| ||||:  |.|.::|   .|..||.|||::.|:.|||:|             ::|:||
Zfish     1 MAEGDK-KKVAR--KHGSRNP---ELVRGIGRYSRSAMFARRAMYKRKTKAPVTKVEKKIKEKK- 58

  Fly    53 PVVEKAKVPIKKVKKIGGPKNGGERTVFLKKSKASYPTKTFVKKRPS---KANFSEHKRNTRRNL 114
             |.:|:|.|...:|.:||.||||.|.|.|:|....|||:...:|..|   || ||:|:|..|:.:
Zfish    59 -VKQKSKNPTTAIKTVGGDKNGGTRVVKLRKMPRYYPTEDVRRKLRSHGIKA-FSQHRRKLRKTI 121

  Fly   115 TPGTVLILLAGRHQGKRVVLLKVLASGLLLVTGPFALNSCPLRRVSQRYVIGTSSKVDLGAFKVP 179
            |||||||:|.|||:|||||.||.|.|||||||||.|:|..||||..|::.|.|::|||:...|:|
Zfish   122 TPGTVLIMLTGRHRGKRVVFLKQLDSGLLLVTGPLAINRVPLRRAHQKFCIATNTKVDISGMKIP 186

  Fly   180 EHLNDAYFRRLKAKKDKKTGEADIFAAKKERFVPNEQRKKDQKEVDAALLKVIKAHPEGKFFAKY 244
            ..|.|:||::.|.:|.|.. |.:||..:||::...||||.|||.||:.||.:||..|:   ...|
Zfish   187 RTLTDSYFKKKKLRKPKHQ-EGEIFDTEKEKYQLTEQRKADQKAVDSQLLPLIKKVPQ---LRGY 247

  Fly   245 LQNMFALHSSQYPHRMRF 262
            |::||:|.:..|||::.|
Zfish   248 LRSMFSLSNGVYPHKLVF 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL6	NP_651876.1	Ribosomal_L6e_N	<23..>51	CDD:281813	12/40 (30%)
		KOW_RPL6	106..262	CDD:240520	79/155 (51%)
		RPL14A	111..234	CDD:225074	67/122 (55%)
rpl6	NP_001003844.2	Ribosomal_L6e_N	6..>48	CDD:281813	19/47 (40%)
		KOW_RPL6	113..265	CDD:240520	79/155 (51%)
		RPL14A	117..241	CDD:225074	68/124 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573348
Domainoid	1	1.000	95	1.000	Domainoid score	I7369
eggNOG	1	0.900	-	-		E1_COG2163
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31001
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3617
OMA	1	1.010	-	-		QHG53785
OrthoDB	1	1.010	-	-		D1227453at2759
OrthoFinder	1	1.000	-	-		FOG0001826
OrthoInspector	1	1.000	-	-		oto41730
orthoMCL	1	0.900	-	-		OOG6_101188
Panther	1	1.100	-	-	LDO	PTHR10715
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1143
SonicParanoid	1	1.000	-	-		X1520
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800