DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL6 and rpl6

DIOPT Version :9

Sequence 1:	NP_651876.1	Gene:	RpL6 / 43723	FlyBaseID:	FBgn0039857	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_588190.1	Gene:	rpl6 / 2539372	PomBaseID:	SPCC622.18	Length:	195	Species:	Schizosaccharomyces pombe

Alignment Length:	199	Identity:	86/199 - (43%)
Similarity:	108/199 - (54%)	Gaps:	11/199 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 KIGGPKNGGERTVFLKKSKAS--YPTKTFVKKRPSKANFSEHKRNTRRNLTPGTVLILLAGRHQG 129
            |:.|.||||||.|......|:  ||  .:.:..|.||..:......|.:|.||||.||||||.:|
pombe     5 KVNGAKNGGERMVLPAGEAAAKYYP--AYRENVPKKARKAVRPTKLRASLAPGTVCILLAGRFRG 67

  Fly   130 KRVVLLKVLASGLLLVTGPFALNSCPLRRVSQRYVIGTSS-KVDLGAFKVPEHLNDAYFRRLKAK 193
            ||||:|..| ...|:||||:.:|..|:|||:.||||.||: |:|:....| |....|||.:.|..
pombe    68 KRVVVLSQL-EDTLVVTGPYKVNGVPIRRVNHRYVIATSAPKIDVSGVSV-EKFTKAYFAKQKRS 130

  Fly   194 KDKKTGEADIFAAKKERFVPNEQRKKDQKEVDAALLKVIKAHPEGKFFAKYLQNMFALHSSQYPH 258
            ...|..|| .||....:.....:|..|||.|||.||..|||.|..|   :||...|||.:...||
pombe   131 GPVKKDEA-FFAENAPKNALPAERIADQKAVDAKLLPAIKAIPNMK---EYLAASFALSNGDRPH 191

  Fly   259 RMRF 262
            .|:|
pombe   192 LMKF 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL6	NP_651876.1	Ribosomal_L6e_N	<23..>51	CDD:281813
		KOW_RPL6	106..262	CDD:240520	70/156 (45%)
		RPL14A	111..234	CDD:225074	58/123 (47%)
rpl6	NP_588190.1	KOW_RPL6	44..195	CDD:240520	70/156 (45%)
rpl6	NP_588190.1	RPL14A	48..171	CDD:225074	59/125 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I2786
eggNOG	1	0.900	-	-		E1_COG2163
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	124	1.000	Inparanoid score	I1475
OMA	1	1.010	-	-		QHG53785
OrthoFinder	1	1.000	-	-		FOG0001826
OrthoInspector	1	1.000	-	-		oto101809
orthoMCL	1	0.900	-	-		OOG6_101188
Panther	1	1.100	-	-	LDO	PTHR10715
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1143
SonicParanoid	1	1.000	-	-		X1520
TreeFam	1	0.960	-	-
	13	12.860