DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1774 and acot9.2

DIOPT Version :9

Sequence 1:	NP_001287623.1	Gene:	CG1774 / 43722	FlyBaseID:	FBgn0039856	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_001032476.1	Gene:	acot9.2 / 798008	ZFINID:	ZDB-GENE-051113-136	Length:	425	Species:	Danio rerio

Alignment Length:	396	Identity:	136/396 - (34%)
Similarity:	214/396 - (54%)	Gaps:	12/396 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 MVEVARVIREQSGVDVGY---HTIPKPRDHLLQHEPK-REELPPRTMLDSHTTAILPLSSSELIR 121
            |.||...:||..|....:   ..:...|..|.|:..: :::||.:.|.||...|.|||.|...:|
Zfish    32 MAEVRNRLREVVGASTNWQDQQQVLSERSSLCQYLARSQDDLPAKRMKDSLIEAHLPLGSQPALR 96

  Fly   122 ESYVNHLGRVRLGRIMEELDMFAVWICHRHVKLPKLPKGVPLPYTFVTLLVDKVEFTNLERLQVN 186
            |.|:|....||.|||:|:||...|.||:.|....:|...   |.:.||.||||::... ..:..:
Zfish    97 EKYLNSHNSVRFGRILEDLDCLGVLICYSHTWNEELQSS---PLSIVTALVDKIDMRQ-NVIYPD 157

  Fly   187 QDIEISGHISWAGRSSMEITIYVRQLAHGEYIDVTKAIFVMVARNATNTGPAPINPIEVGDETEK 251
            .||:.:||::|.|::|:|..:::.|..:|.|.|:..|.||||||:..|...|.:||::...:.|:
Zfish   158 CDIKFTGHVTWVGKTSIEAKMHMSQYQNGTYADLLDATFVMVARDPENKRAAFVNPLKPVGQEEE 222

  Fly   252 LIWEQAE--KRQKVRKSSAMDSVFNSPPREHEQALMYEILKRTTPANSMDLNKRVLPPKCRWMED 314
            .|:.|.|  |:::|..|:|  |:....|...|:.|::.....|....::....|:|||...||||
Zfish   223 AIFLQGEINKKRRVELSTA--SLLKVAPTAEERTLIHNQFLNTLDTRTVSFRSRILPPNSVWMED 285

  Fly   315 SMQSTMIAPFPENRNAQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDISFMHPVHVDRFL 379
            :....:....|:.||..|.||||:|||:|.|:....|..:.|.|||:..:.||.|..||.:...|
Zfish   286 AKLKGLEICHPQERNIFNRIFGGFLMRKAYELGRANACAFAGCRPTVVAVDDILFRKPVEIGSLL 350

  Fly   380 QLTAHVVYAAQNYVQLMTVAQIWDAKSGKVQTTNVFYLTYRADKVLDEVLPRSYREMLWYVHGRR 444
            .|::.|.|....|||:...:::.|..:.:..|||||:.|:|.:|.:..|:|:||.|.:.|:.|:|
Zfish   351 LLSSQVCYTEGMYVQVRVHSEVLDPLTRQHSTTNVFHFTFRLEKEVPAVVPQSYGESMLYLDGKR 415

  Fly   445 KLLGAL 450
            ...||:
Zfish   416 HFDGAM 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1774	NP_001287623.1	BFIT_BACH	107..241	CDD:239526	50/133 (38%)
CG1774	NP_001287623.1	BFIT_BACH	310..421	CDD:239526	41/110 (37%)
acot9.2	NP_001032476.1	BFIT_BACH	84..209	CDD:239526	49/128 (38%)
acot9.2	NP_001032476.1	BFIT_BACH	281..401	CDD:239526	44/119 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586473
Domainoid	1	1.000	269	1.000	Domainoid score	I1798
eggNOG	1	0.900	-	-		E1_COG1607
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8206
Inparanoid	1	1.050	269	1.000	Inparanoid score	I2990
OMA	1	1.010	-	-		QHG55517
OrthoDB	1	1.010	-	-		D261460at33208
OrthoFinder	1	1.000	-	-		FOG0002448
OrthoInspector	1	1.000	-	-		mtm6591
orthoMCL	1	0.900	-	-		OOG6_102325
Panther	1	1.100	-	-	O	PTHR12655
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1631
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770