DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1774 and Acot12

DIOPT Version :9

Sequence 1:	NP_001287623.1	Gene:	CG1774 / 43722	FlyBaseID:	FBgn0039856	Length:	472	Species:	Drosophila melanogaster
Sequence 2:	NP_083066.1	Gene:	Acot12 / 74156	MGIID:	1921406	Length:	556	Species:	Mus musculus

Alignment Length:	347	Identity:	73/347 - (21%)
Similarity:	133/347 - (38%)	Gaps:	62/347 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 SELIRESYVNHLGRVRLGRIMEELDMFAVWICHRHVKLPKLPKGVPLPYTFVTLLVDKVEFTNLE 181
            |:.|:.::.:..|.:..|::::.:|..|.....:|..:           :.||..:|.:.|.:..
Mouse    13 SQAIQPAHADSRGELSAGQLLKWMDTTACLAAEKHAGI-----------SCVTASMDDILFEDTA 66

  Fly   182 RLQVNQDIEISGHISWAGRSSMEITIYVRQLAHGEYIDVTKAIFV----MVARNATNTGPAPINP 242
            |  :.|.|.|...::.|..:||||:|.|  :...::..:.|.:.|    .||: ........:.|
Mouse    67 R--IGQIITIRAKVTRAFSTSMEISIKV--IVQDKFTGIQKLLCVAFSTFVAK-PVGKEKVHLKP 126

  Fly   243 IEVGDETEKLIWEQAEKRQKVR--KSSAMDSVFNSPPREHEQALMYEILKRTTPANSMDLNKRVL 305
            :.:..|.|::....|.:|:|||  ..:..:::.....|..:.....|....||...|:...:.||
Mouse   127 VLLQTEQEQVEHNLASERRKVRLQHENTFNNIMKESSRFSDSICNEEEGTATTMGTSVQSIELVL 191

  Fly   306 PPKCRWMEDSMQSTMIAPFPENRNAQNTIFGGYLMRQAVEISFIMASIYLGDRPTLRCISDISFM 370
            ||                   :.|.....|||.:|.....::.|.||......|.|:.:....|.
Mouse   192 PP-------------------HANHHGNTFGGQIMAWMETVATISASRLCHGHPFLKSVDMFKFR 237

  Fly   371 HPVHVDRFLQLTAHVVYAAQNYVQLMTVAQIWDAK---SGKVQTTNVFYLTYRADKVLDEVLPRS 432
            .|..|...|..:|.|....||.|::....:.:|.:   .|:.:..|..:|.|.|
Mouse   238 GPSTVGDRLVFSAIVNNTFQNSVEVGVRVEAFDCQEWAEGQGRHINSAFLIYNA----------- 291

  Fly   433 YREMLWYVHGRRKLLGALHLQP 454
                   |..:.||:....:||
Mouse   292 -------VDDQEKLITFPRIQP 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1774	NP_001287623.1	BFIT_BACH	107..241	CDD:239526	26/127 (20%)
CG1774	NP_001287623.1	BFIT_BACH	310..421	CDD:239526	24/113 (21%)
Acot12	NP_083066.1	BFIT_BACH	4..116	CDD:239526	26/118 (22%)
		Coenzyme A binding. /evidence=ECO:0000250	54..56		1/1 (100%)
		Coenzyme A binding. /evidence=ECO:0000250	83..85		0/1 (0%)
		BFIT_BACH	182..306	CDD:239526	33/160 (21%)
		Coenzyme A binding. /evidence=ECO:0000250	235..237		0/1 (0%)
		SRPBCC	312..547	CDD:387369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1607
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810